Title:
NOVEL POLYPEPTIDE SELECTIVELY BINDING TO HUMAN PROGRAMMED CELL DEATH PROTEIN (PD-1) AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/040336
Kind Code:
A1
Abstract:
The present invention relates to a novel polypeptide which can specifically bind to programmed cell death protein 1, a polynucleotide coding for the polypeptide, a vector comprising the polynucleotide, a recombinant microorganism in which the expression vector has been introduced, a method for preparing the polypeptide by means of the recombinant microorganism, a cancer preventing or treating composition comprising the polypeptide, and a cancer prevention or treatment method comprising administration of the cancer preventing or treating composition comprising the polypeptide. The polypeptide of the present invention can inhibit the activity of programmed cell death protein 1 by binding thereto and thus can be widely utilized for a formulation for preventing or treating various diseases associated with programmed cell death protein 1.
Inventors:
KIM HAK-SUNG (KR)
SON SUMIN (KR)
SEO HYO-DEOK (KR)
PARK JINHO (KR)
SON SUMIN (KR)
SEO HYO-DEOK (KR)
PARK JINHO (KR)
Application Number:
PCT/KR2020/011193
Publication Date:
March 04, 2021
Filing Date:
August 21, 2020
Export Citation:
Assignee:
KOREA ADVANCED INST SCI & TECH (KR)
International Classes:
C07K16/28; A61K39/00; A61P35/00
Foreign References:
| KR20150135700A | 2015-12-03 | |||
| KR20130098089A | 2013-09-04 | |||
| US20140088292A1 | 2014-03-27 | |||
| KR20170069996A | 2017-06-21 |
Other References:
SUMIN SON, HYO-DEOK SEO, HAK-SUNG KIM: "Development of Human PDâ1 Specific Repebody for Cancer Immunotherapy", 2019 KSBB SPRING MEETING; APRIL 10-12, 2019, April 2019 (2019-04-01), pages 407, XP009526446
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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