Title:
NOVEL TREATMENT AND PREVENTION BASED ON NOVEL METHOD FOR REGULATING CELLULAR IMMUNITY
Document Type and Number:
WIPO Patent Application WO/2022/176068
Kind Code:
A1
Abstract:
The present disclosure provides a composition for preventing or treating a disease (for example, an infectious, allergic or autoimmune disease). The present disclosure provides a composition, a medicine, a kit, etc. for preventing or treating the aforesaid disease of a subject. The composition, medicine, kit, etc. are characterized by containing a non-causative factor antigen component, which is neither derived from the causative factor of the disease nor cross-reactive with the causative factor, and being to be administered under conditions where a causative factor antigen component derived from the causative factor of the target disease and/or cross-reactive with the causative factor is present in the subject.
Inventors:
ISHII KEN (JP)
TEMIZOZ BURCU (JP)
KATSUNUMA KOKICHI (JP)
TEMIZOZ BURCU (JP)
KATSUNUMA KOKICHI (JP)
Application Number:
PCT/JP2021/005951
Publication Date:
August 25, 2022
Filing Date:
February 17, 2021
Export Citation:
Assignee:
ZERIA PHARM CO LTD (JP)
ISHII KEN (JP)
ISHII KEN (JP)
International Classes:
A61K39/04; A61K39/00; A61K39/002; A61K39/02; A61K39/12; A61K39/215; A61K39/35; A61P31/00; A61P31/12; A61P31/14; A61P37/04; A61P37/08
Domestic Patent References:
| WO1999045917A1 | 1999-09-16 | |||
| WO2000053203A1 | 2000-09-14 |
Other References:
COUNOUPAS CLAUDIO, JOHANSEN MATT D., STELLA ALBERTO O., NGUYEN DUC H., FERGUSON ANGELA L., AGGARWAL ANUPRIYA, BHATTACHARYYA NAYAN : "A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilizing immunity against SARS-CoV-2 infection in mice", BIORXIV, 10 December 2020 (2020-12-10), pages 1 - 25, XP055959457, Retrieved from the Internet [retrieved on 20220909], DOI: 10.1101/2020.12.10.419044
SUSAN M. BUENO, PABLO A. GONZALEZ, KELLY M. CAUTIVO, JORGE E. MORA, EDUARDO D. LEIVA, HUGO E. TOBAR, GLENN J. FENNELLY, ELISEO A. : "Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, vol. 105, no. 52, 30 December 2008 (2008-12-30), pages 20822 - 20827, XP002694159, ISSN: 0027-8424, DOI: 10.1073/pnas.0806244105
LEENTJENS JENNEKE, KOX MATTHIJS, STOKMAN ROBIN, GERRETSEN JELLE, DIAVATOPOULOS DIMITRI A., VAN CREVEL REINOUT, RIMMELZWAAN GUUS F.: "BCG Vaccination Enhances the Immunogenicity of Subsequent Influenza Vaccination in Healthy Volunteers: A Randomized, Placebo-Controlled Pilot Study", JOURNAL OF INFECTIOUS DISEASES, UNIVERSITY OF CHICAGO PRESS, US, vol. 212, no. 12, 15 December 2015 (2015-12-15), US , pages 1930 - 1938, XP055959469, ISSN: 0022-1899, DOI: 10.1093/infdis/jiv332
KOBAYASHI, M. ; HERNDON, D.N. ; POLLARD, R.B. ; SUZUKI, F.: "Z-100, a lipid-arabinomannan extracted from Mycobacterium tuberculosis, improves the resistance of thermally injured mice to herpes virus infections", IMMUNOLOGY LETTERS, ELSEVIER BV, NL, vol. 40, no. 3, 1 June 1994 (1994-06-01), NL , pages 199 - 205, XP023692849, ISSN: 0165-2478, DOI: 10.1016/0165-2478(93)00018-9
SAŁKOWSKA ANNA, KARWACIAK IWONA, KARAŚ KAJA, DASTYCH JAROSŁAW, RATAJEWSKI MARCIN: "SARS-CoV-2 Proteins Induce IFNG in Th1 Lymphocytes Generated from CD4+ Cells from Healthy, Unexposed Polish Donors", VACCINES, vol. 8, no. 4, 1 January 2020 (2020-01-01), pages 1 - 10, XP055959477, DOI: 10.3390/vaccines8040673
SUSAN M. BUENO, PABLO A. GONZALEZ, KELLY M. CAUTIVO, JORGE E. MORA, EDUARDO D. LEIVA, HUGO E. TOBAR, GLENN J. FENNELLY, ELISEO A. : "Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, vol. 105, no. 52, 30 December 2008 (2008-12-30), pages 20822 - 20827, XP002694159, ISSN: 0027-8424, DOI: 10.1073/pnas.0806244105
LEENTJENS JENNEKE, KOX MATTHIJS, STOKMAN ROBIN, GERRETSEN JELLE, DIAVATOPOULOS DIMITRI A., VAN CREVEL REINOUT, RIMMELZWAAN GUUS F.: "BCG Vaccination Enhances the Immunogenicity of Subsequent Influenza Vaccination in Healthy Volunteers: A Randomized, Placebo-Controlled Pilot Study", JOURNAL OF INFECTIOUS DISEASES, UNIVERSITY OF CHICAGO PRESS, US, vol. 212, no. 12, 15 December 2015 (2015-12-15), US , pages 1930 - 1938, XP055959469, ISSN: 0022-1899, DOI: 10.1093/infdis/jiv332
KOBAYASHI, M. ; HERNDON, D.N. ; POLLARD, R.B. ; SUZUKI, F.: "Z-100, a lipid-arabinomannan extracted from Mycobacterium tuberculosis, improves the resistance of thermally injured mice to herpes virus infections", IMMUNOLOGY LETTERS, ELSEVIER BV, NL, vol. 40, no. 3, 1 June 1994 (1994-06-01), NL , pages 199 - 205, XP023692849, ISSN: 0165-2478, DOI: 10.1016/0165-2478(93)00018-9
SAŁKOWSKA ANNA, KARWACIAK IWONA, KARAŚ KAJA, DASTYCH JAROSŁAW, RATAJEWSKI MARCIN: "SARS-CoV-2 Proteins Induce IFNG in Th1 Lymphocytes Generated from CD4+ Cells from Healthy, Unexposed Polish Donors", VACCINES, vol. 8, no. 4, 1 January 2020 (2020-01-01), pages 1 - 10, XP055959477, DOI: 10.3390/vaccines8040673
Attorney, Agent or Firm:
YAMAMOTO, Shusaku et al. (JP)
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