Title:
NUCLEIC ACID VECTOR, METHOD FOR PREPARATION THEREOF, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/019872
Kind Code:
A1
Abstract:
Provided are a polypeptide nucleic acid vector containing a cell-penetrating peptide and an antimicrobial peptide having an α-helix amphiphilic structure. Also provided are a composite containing said nucleic acid vector and nucleic acid molecule, and a method for preparation of said nucleic acid vector and composite, and a use of said nucleic acid vector and composite.
Inventors:
LIU KELIANG (CN)
LUAN LIANG (CN)
XU LIANG (CN)
MENG QINGBIN (CN)
XU XIAOYU (CN)
JIA QIYAN (CN)
LUAN LIANG (CN)
XU LIANG (CN)
MENG QINGBIN (CN)
XU XIAOYU (CN)
JIA QIYAN (CN)
Application Number:
PCT/CN2015/086134
Publication Date:
February 11, 2016
Filing Date:
August 05, 2015
Export Citation:
Assignee:
INST PHARM & TOXICOLOGY AMMS (CN)
International Classes:
C12N15/63; A61K47/48; A61K48/00; A61P35/00; C07K19/00; C12N5/10
Foreign References:
| CN101381741A | 2009-03-11 |
Other References:
LIU, SHAN ET AL.: "Enhancement of Cytotocixity of Cantionic Antimicrobial Peptide in Tumor Cells by Conjugation to Cell -penetrating Peptide", JOURNAL OF BIOMEDICAL ENGINEERING, vol. 28, no. 1, 28 February 2011 (2011-02-28), pages 110 - 114, ISSN: 1001-5515
XU, JIAPING ET AL.: "Progress of Multifunctional Antimicrobial Peptides and Its Molecular Design", PROCEEDINGS OF 12TH SILKWORM EGG SEMINAR IN EASTERN AND CENTRAL CHINA REGIONS, 31 December 2010 (2010-12-31), pages 282 - 289
XU, JIAPING ET AL.: "Progress of Multifunctional Antimicrobial Peptides and Its Molecular Design", PROCEEDINGS OF 12TH SILKWORM EGG SEMINAR IN EASTERN AND CENTRAL CHINA REGIONS, 31 December 2010 (2010-12-31), pages 282 - 289
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
中国国际贸易促进委员会专利商标事务所 (CN)
Download PDF: