Title:
OINTMENT COMPOSITION FOR IMPROVING PERIODONTITIS
Document Type and Number:
WIPO Patent Application WO/2018/124324
Kind Code:
A1
Abstract:
The present invention relates to an ointment composition for improving periodontitis and, more specifically, to an ointment composition for improving periodontitis, capable of effectively preventing or treating periodontitis by containing as a core ingredient minocycline hydrochloride, which has high sensitivity to periodontitis-related bacteria and can exhibit a continuous antibacterial action through the adsorption to the calcium on a tooth surface. To this end, the present invention contains 1.0-2.5 wt% of minocycline hydrochloride, 75.5-82.5 wt% of a base, 14.4-18.5 wt% of a thickening agent, 0.1-0.5 wt% of an antioxidant, and 2.0-3.0 wt% of a stabilizer, the base being any one or a mixture of two or more of glycerin, polyethylene glycol 400, and polyethylene glycol 6000, the thickening agent being any one or a mixture of two or more of hydroxyethyl cellulose, acrylate/octylacrylamide copolymer, and hydroxypropyl cellulose 2208, the antioxidant being any one selected from butyl hydroxy toluene or tocopheryl acetate.
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Inventors:
SHIN JIN WOOK (KR)
HONG JU HYUN (KR)
AHN JI HAE (KR)
LIM JONG YOUNG (KR)
HONG JU HYUN (KR)
AHN JI HAE (KR)
LIM JONG YOUNG (KR)
Application Number:
PCT/KR2016/015347
Publication Date:
July 05, 2018
Filing Date:
December 27, 2016
Export Citation:
Assignee:
KUWOTECH CO LTD (KR)
International Classes:
A61K9/06; A61K31/65; A61K47/06; A61K47/10
Foreign References:
| US4701320A | 1987-10-20 | |||
| KR20130070307A | 2013-06-27 | |||
| KR19990075100A | 1999-10-05 | |||
| KR20010107662A | 2001-12-07 | |||
| KR20010096065A | 2001-11-07 |
Attorney, Agent or Firm:
SHINSEGI PATENT LAW FIRM (KR)
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