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Title:
OPIOID SUSTAINED-RELEASED FORMULATION
Document Type and Number:
WIPO Patent Application WO2001008661
Kind Code:
A3
Abstract:
A solid, oral, controlled release dosage form comprising a therapeutically effective amount of an opioid compound, or a salt thereof, a matrix-forming polymer and an ionic exchange resin.

Inventors:
MALONEY ANN M
Application Number:
PCT/US2000/020413
Publication Date:
March 22, 2001
Filing Date:
July 27, 2000
Export Citation:
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Assignee:
ROXANE LAB INC (US)
International Classes:
A61K9/20; A61K9/22; A61K9/26; C07D489/08; A61K9/28; A61K31/135; A61K31/216; A61K31/439; A61K31/451; A61K31/485; A61K47/30; A61K47/32; A61K47/34; A61K47/38; A61K47/48; A61P25/04; (IPC1-7): A61K9/20; A61K47/48; A61K31/485
Foreign References:
US4859461A1989-08-22
GB2176999A1987-01-14
US5709882A1998-01-20
Other References:
SRIWONGJANYA M ET AL: "EFFECT OF ION EXCHANGE RESINS ON THE DRUG RELEASE FROM MATRIX TABLETS", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,NL,ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, vol. 46, no. 3, 1 November 1998 (1998-11-01), pages 321 - 327, XP000787137, ISSN: 0939-6411
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