Title:
ORAL FORMULATION COMPRISING 1-(3-CYANO-1-ISOPROPYL-INDOLE-5-YL)PYRAZOLE-4-CARBOXYLIC ACID AND METHOD FOR PREPARING SAME
Document Type and Number:
WIPO Patent Application WO/2022/119270
Kind Code:
A1
Abstract:
The present invention relates to an oral formulation comprising a high content of an API selected from 1-(3-cyano-1-isopropyl-indole-5-yl)pyrazole-4-carboxylic acid or a pharmaceutically acceptable salt thereof. The oral formulation according to the present invention has a high content and excellent physical properties by comprising a fluidizing agent from among excipients, and thus can have increased economic efficiency and convenience of administration.
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Inventors:
YOO SEOK CHEOL (KR)
JANG JOOMYUNG (KR)
KIM REE SUN (KR)
SEO JIN A (KR)
JANG JOOMYUNG (KR)
KIM REE SUN (KR)
SEO JIN A (KR)
Application Number:
PCT/KR2021/017843
Publication Date:
June 09, 2022
Filing Date:
November 30, 2021
Export Citation:
Assignee:
LG CHEMICAL LTD (KR)
International Classes:
A61K9/20; A61K31/4155
Foreign References:
| KR20120114174A | 2012-10-16 | |||
| US5879706A | 1999-03-09 | |||
| KR20110037883A | 2011-04-13 | |||
| KR20090128488A | 2009-12-15 | |||
| KR20200165790A | ||||
| KR101751325B1 | 2017-06-27 | |||
| KR101424013B1 | 2014-08-18 |
Other References:
MAJEROVá DIANA; KULAVIAK LUKáš; RůžIčKA MAREK; ŠTěPáNEK FRANTIšEK; ZáMOSTN&: "Effect of colloidal silica on rheological properties of common pharmaceutical excipients", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM., NL, vol. 106, 7 May 2016 (2016-05-07), NL , pages 2 - 8, XP029677539, ISSN: 0939-6411, DOI: 10.1016/j.ejpb.2016.04.025
See also references of EP 4257124A4
See also references of EP 4257124A4
Attorney, Agent or Firm:
KIM, Sung Ho (KR)
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