Title:
ORALLY DISINTEGRATING TABLET
Document Type and Number:
WIPO Patent Application WO/2019/064468
Kind Code:
A1
Abstract:
An orally disintegrating tablet which comprises zonisamide as an active ingredient and is free from crystalline cellulose or corn starch but contains crospovidone and low substituted hydroxypropylcellulose as pharmaceutical additives, wherein the content of crospovidone is 1-10 mass% inclusive relative to the total mass of the tablet. In the orally disintegrating tablet, a decrease in hygroscopicity and deterioration in dissolution properties following moisture absorption are avoided.
Inventors:
HORAGUCHI HARUHIKO (JP)
YOSHIMURA KATSUHIRO (JP)
YOSHIMURA KATSUHIRO (JP)
Application Number:
PCT/JP2017/035381
Publication Date:
April 04, 2019
Filing Date:
September 29, 2017
Export Citation:
Assignee:
TEVA TAKEDA PHARMA LTD (JP)
International Classes:
A61K31/423; A61K9/20; A61K47/32; A61K47/38; A61P25/16
Domestic Patent References:
| WO2009102038A1 | 2009-08-20 |
Foreign References:
| JP2012036140A | 2012-02-23 | |||
| JPH03130214A | 1991-06-04 | |||
| JP2017165768A | 2017-09-21 | |||
| CN107095853A | 2017-08-29 |
Other References:
TAKATORI TOSHIHITO: "TRelief OD Tablets 25mg. Farumashia", THE SCIENCE OF PHARMACEUTICAL PRODUCTION; IN SEARCH OF CLINICALLY USEABLE MEDICINE, vol. 53, no. 52, 1 February 2017 (2017-02-01), pages 167 - 169
Attorney, Agent or Firm:
SIKS & CO. (JP)
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