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Title:
PROMOTER OF Eno1 GENE
Document Type and Number:
WIPO Patent Application WO/2023/210607
Kind Code:
A1
Abstract:
Provided is a promoter having high foreign gene expression enhancement activity in a host cell such as a mammalian cultured cell. As a means for increasing the production amount of a foreign protein to be used as a proteinaceous pharmaceutical product by using said promoter, provided is a polynucleotide which is a promoter of a gene derived from a Chinese hamster, and contains: a nucleotide sequence that is selected from among SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, and SEQ ID NO: 14, or shares a sequence identity of at least 85% with the sequences thereof; or a partial sequence of said nucleotide sequence.

Inventors:
NISHIO MAUI (JP)
NAKAZAWA YUTO (JP)
KAMIZONO SHOTARO (JP)
Application Number:
PCT/JP2023/016191
Publication Date:
November 02, 2023
Filing Date:
April 25, 2023
Export Citation:
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Assignee:
DAIICHI SANKYO CO LTD (JP)
International Classes:
C12N15/11; C12N5/10; C12N15/13; C12N15/63; C12P21/02; C12P21/08
Domestic Patent References:
WO2020032153A12020-02-13
WO2018066492A12018-04-12
Attorney, Agent or Firm:
OHNO Seiji et al. (JP)
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