Title:
PARENTERAL LIQUID PREPARATION COMPRISING CARBAMATE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2018/111000
Kind Code:
A1
Abstract:
The present invention relates to a parenteral liquid preparation containing, as active ingredients; a carbamate compound of chemical formula 1, an isomer thereof, or a pharmaceutically acceptable salt, a solvate or a hydrate thereof; and a cyclodextrin derivative.
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Inventors:
BAEK MYOUNG KI (KR)
LEE JI HYE (KR)
CHOI SO YOUNG (KR)
LEE JI HYE (KR)
CHOI SO YOUNG (KR)
Application Number:
PCT/KR2017/014727
Publication Date:
June 21, 2018
Filing Date:
December 14, 2017
Export Citation:
Assignee:
SK BIOPHARMACEUTICALS CO LTD (KR)
International Classes:
A61K9/08; A61K9/00; A61K31/325; A61K31/41; A61K47/40
Domestic Patent References:
| WO2006112685A1 | 2006-10-26 | |||
| WO2010150946A1 | 2010-12-29 | |||
| WO2011046380A2 | 2011-04-21 | |||
| WO2010150946A1 | 2010-12-29 |
Foreign References:
| US20060258718A1 | 2006-11-16 |
Other References:
RAJEWSKI, R. A. ET AL.: "Pharmaceutical Applications of Cyclodextrins. 2. In Vivo Drug Delivery", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 85, no. 11, 1996, pages 1142 - 1169, XP000629515
LOSCHER, W. ET AL.: "New Injectable Aqueous Carbamazepine Solution Through Complexing with 2-Hydroxypropyl-13-Cyclodextrin: Tolerability and Pharmacokinetics After Intravenous Injection in Comparison to a Glycofurol-Based Formulation", EPILEPSIA, vol. 36, no. 3, 1995, pages 255 - 261, XP055428288
GOULD, S. ET AL.: "2-Hydroxypropyl-beta-cyclodextrin (HP-beta- CD ): a Toxicology Review", FOOD AND CHEMICAL TOXICOLOGY, vol. 43, 2005, pages 1451 - 1459, XP004976497
HOLVOET, C. ET AL.: "Inclusion Complexation of Lorazepam with Different Cyclodextrins Suitable for Parenteral Use", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol. 31, 2005, pages 567 - 575, XP055510488
FAIRCHILD, E.J.R.J. LEWIS, JR.R.L. TATKEN: "Registry of Toxic Effects of Chemical Substances", vol. II, 1977, DHEW PUBL.
GERSHANIK JBOECLER BENSLEY HMCCLOSKEY SGEORGE W: "The gasping syndrome and benzyl alcohol poisoning", NEW ENGLAND JOURNAL OF MEDICINE, vol. 307, no. 22, 1982, pages 1384 - 8
T. IRIEK. UEKAMA: "Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation", J. PHARM. SCI., vol. 86, no. 2, 1997, pages 147 - 162, XP000643007, DOI: doi:10.1021/js960213f
S. GOULDR. C. SCOTT: "2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD): a toxicology review", FOOD CHEM TOXICOL., vol. 43, no. 10, 2005, pages 1451 - 1459, XP027602389
See also references of EP 3556349A4
LOSCHER, W. ET AL.: "New Injectable Aqueous Carbamazepine Solution Through Complexing with 2-Hydroxypropyl-13-Cyclodextrin: Tolerability and Pharmacokinetics After Intravenous Injection in Comparison to a Glycofurol-Based Formulation", EPILEPSIA, vol. 36, no. 3, 1995, pages 255 - 261, XP055428288
GOULD, S. ET AL.: "2-Hydroxypropyl-beta-cyclodextrin (HP-beta- CD ): a Toxicology Review", FOOD AND CHEMICAL TOXICOLOGY, vol. 43, 2005, pages 1451 - 1459, XP004976497
HOLVOET, C. ET AL.: "Inclusion Complexation of Lorazepam with Different Cyclodextrins Suitable for Parenteral Use", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, vol. 31, 2005, pages 567 - 575, XP055510488
FAIRCHILD, E.J.R.J. LEWIS, JR.R.L. TATKEN: "Registry of Toxic Effects of Chemical Substances", vol. II, 1977, DHEW PUBL.
GERSHANIK JBOECLER BENSLEY HMCCLOSKEY SGEORGE W: "The gasping syndrome and benzyl alcohol poisoning", NEW ENGLAND JOURNAL OF MEDICINE, vol. 307, no. 22, 1982, pages 1384 - 8
T. IRIEK. UEKAMA: "Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation", J. PHARM. SCI., vol. 86, no. 2, 1997, pages 147 - 162, XP000643007, DOI: doi:10.1021/js960213f
S. GOULDR. C. SCOTT: "2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD): a toxicology review", FOOD CHEM TOXICOL., vol. 43, no. 10, 2005, pages 1451 - 1459, XP027602389
See also references of EP 3556349A4
Attorney, Agent or Firm:
HANSUNG INTELLECTUAL PROPERTY (KR)
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