PARTICLE SIZER AND DNA SEQUENCER

Title:

PARTICLE SIZER AND DNA SEQUENCER

Document Type and Number:

WIPO Patent Application WO2002059273

Kind Code:

A3

Abstract:

The electrophoresis device (110) has a capillary (112) which is coated with a cowing with a low refractive index such as Teflon AF. A sample of particles is fluorescently labeled and injected into the capillary (112). The capilary (112) is filled with an electrolyte buffer solution. An electrical field is applied across the capillary (112) causing the particles to migrate from a first end of the capillary (112) to a second end of the capillary (112). A detector light beam (114) is then scanned along the length of the capillary (112) to detect the location of the separated particles. The device (110) is amenable to a high throughput system by providing additional capillaries (112).

Inventors:

OLIVARES JOSE A
STARK PETER C

Application Number:

PCT/US2002/002204

Publication Date:

August 21, 2003

Filing Date:

January 24, 2002

Export Citation:

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Assignee:

UNIV CALIFORNIA (US)

International Classes:

G01N15/14; G01N21/03; G01N27/447; C12Q1/68; (IPC1-7): G01N27/26; G01N27/447

Foreign References:

US5395502A	1995-03-07
US5627643A	1997-05-06
US5694215A	1997-12-02
US5699157A	1997-12-16
US6042708A	2000-03-28

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