Title:
PENICILLIN REFINING SYSTEM AND REFINING METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/082619
Kind Code:
A1
Abstract:
The present invention provides a penicillin refining system and a refining method therefor. The penicillin refining system comprises: a fermentation tank and a control system, wherein the top portion of the fermentation tank is provided with a bacterial solution inlet and a feed liquid inlet for bacterial solution and feed liquid to enter, and the bottom portion of the fermentation tank is provided with a liquid outlet for discharging a fermentation product; and liquid ejectors and micro-interface generators are arranged in the fermentation tank, the micro-interface generator located on an upper portion is close to the top portion of the fermentation tank, the micro-interface generator located on a lower portion is close to the bottom portion of the fermentation tank, the liquid ejectors are arranged on an upper portion in the fermentation tank, two liquid ejectors are arranged on side walls of the fermentation tank respectively, and another liquid ejector is arranged opposite the upper micro-interface generator. The refining method comprises the following steps: breaking up cleaning water into micron-sized micro-droplets to clean the interior of a fermentation tank; and dispersing and breaking up an air micro-interface, mixing the air micro-interface with a bacterial solution and feed liquid for aerobic fermentation, and discharging and collecting a fermentation product. The penicillin refining system solves the problem in the prior art of low fermentation efficiency due to the fact that air and fermentation liquid cannot be fully mixed in a fermentation tank, and saves on the labor cost for cleaning and field operations.
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Inventors:
ZHANG ZHIBING (CN)
ZHOU ZHENG (CN)
ZHANG FENG (CN)
LI LEI (CN)
MENG WEIMIN (CN)
WANG BAORONG (CN)
YANG GAODONG (CN)
LUO HUAXUN (CN)
YANG GUOQIANG (CN)
TIAN HONGZHOU (CN)
CAO YU (CN)
ZHOU ZHENG (CN)
ZHANG FENG (CN)
LI LEI (CN)
MENG WEIMIN (CN)
WANG BAORONG (CN)
YANG GAODONG (CN)
LUO HUAXUN (CN)
YANG GUOQIANG (CN)
TIAN HONGZHOU (CN)
CAO YU (CN)
Application Number:
PCT/CN2020/122874
Publication Date:
April 28, 2022
Filing Date:
October 22, 2020
Export Citation:
Assignee:
NANJING YANCHANG REACTION TECH RESEARCH INSTITUTE CO LTD (CN)
International Classes:
C12M1/00; C12P37/00; C12M1/36
Foreign References:
| CN210103906U | 2020-02-21 | |||
| CN111643702A | 2020-09-11 | |||
| CN105903425A | 2016-08-31 | |||
| CN202909140U | 2013-05-01 | |||
| CN204723426U | 2015-10-28 |
Attorney, Agent or Firm:
BEIJING ZHONGSUO INTELLECTUAL PROPERTY AGENCY CO. LTD (CN)
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