Title:
PEPTIDE COMPOUND, APPLICATION THEREOF AND COMPOSITION CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO/2019/001459
Kind Code:
A1
Abstract:
Disclosed in the present invention are a peptide compound, an application thereof, and a composition containing the same. Provided in the present invention are a peptide compound represented by formula I, a pharmaceutically acceptable salt thereof, a tautomer thereof, a solvate thereof, a crystal form thereof, or a prodrug thereof. The compound has good stability and good activity.
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Inventors:
WANG YAN (CN)
ANGELL YVONNE (CN)
WU YUN (CN)
LI MANHUA (CN)
HU YONGHAN (CN)
ANGELL YVONNE (CN)
WU YUN (CN)
LI MANHUA (CN)
HU YONGHAN (CN)
Application Number:
PCT/CN2018/093088
Publication Date:
January 03, 2019
Filing Date:
June 27, 2018
Export Citation:
Assignee:
XDCEXPLORER SHANGHAI CO LTD (CN)
International Classes:
C07K7/00; A61K38/00; A61P3/00; A61P29/00; A61P37/00
Domestic Patent References:
| WO2013117581A1 | 2013-08-15 |
Foreign References:
| JP2010229093A | 2010-10-14 | |||
| CN201710502668A | 2017-06-27 | |||
| CN201810662539A | 2018-06-25 | |||
| JP2010229093A | 2010-10-14 |
Other References:
SHIMAMURA, K. ET AL.: "Identification of a Stable Chemerin Analog with Potent Activity Toward ChemR23", PEPTIDES, vol. 30, 20 June 2009 (2009-06-20), XP055061081
ROH, S.G. ET AL.: "Physiological Roles of Adipokines, Hepatokines, and Myokines in Ruminants", ASIAN-AUST. J. ANIM. SCI., vol. 29, no. 1, 31 January 2016 (2016-01-31), XP055562593
SUZUKI, Y. ET AL.: "The Regulation of Chemerin and CMKLR1 Genes Expression by TNF-#, Adiponectin, and Chemerin Analog in Bovine Differentiated Adipocytes", ASIAN-AUST. J. ANIM. SCI., vol. 25, no. 9, 30 September 2012 (2012-09-30), XP055562595
"Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
J. RAUTIO ET AL., NATURE REVIEWS DRUG DISCOVERY, vol. 7, 2008, pages 255 - 270
"rodrugs: Challenges and Rewards", 2007, SPRINGER
LU ET AL., J.ORG. CHEM., vol. 46, 1981, pages 3433
See also references of EP 3647319A4
ROH, S.G. ET AL.: "Physiological Roles of Adipokines, Hepatokines, and Myokines in Ruminants", ASIAN-AUST. J. ANIM. SCI., vol. 29, no. 1, 31 January 2016 (2016-01-31), XP055562593
SUZUKI, Y. ET AL.: "The Regulation of Chemerin and CMKLR1 Genes Expression by TNF-#, Adiponectin, and Chemerin Analog in Bovine Differentiated Adipocytes", ASIAN-AUST. J. ANIM. SCI., vol. 25, no. 9, 30 September 2012 (2012-09-30), XP055562595
"Handbook of Pharmaceutical Salts: Properties, Selection, and Use", 2002, WILEY-VCH
J. RAUTIO ET AL., NATURE REVIEWS DRUG DISCOVERY, vol. 7, 2008, pages 255 - 270
"rodrugs: Challenges and Rewards", 2007, SPRINGER
LU ET AL., J.ORG. CHEM., vol. 46, 1981, pages 3433
See also references of EP 3647319A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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