Title:
PEPTIDE DERIVED FROM BARTONELLA SPP.
Document Type and Number:
WIPO Patent Application WO/2023/167340
Kind Code:
A1
Abstract:
The present invention relates to a chimeric peptide containing a first domain and a second domain, wherein the first domain contains (i) a peptide containing at least an amino acid sequence shown by any of ID SEQ NOS: 1-4, (ii) a peptide containing an amino acid sequence having 80% or more identity with an amino acid sequence shown by any of ID SEQ NOS: 1-4, or (ii) a peptide containing an amino acid sequence having one or several amino acids of an amino acid sequence shown by any of ID SEQ NOS: 1-4 added, substituted, or deleted and the second domain contains (i) a peptide containing at least an amino acid sequence shown by any of SEQ ID NOS: 5-12, (ii) a peptide containing an amino acid sequence having 80% or more identity with an amino acid sequence shown by any of ID SEQ NOS: 5-12, or (iii) ) a peptide containing an amino acid sequence having one or several amino acids of an amino acid sequence shown by any of ID SEQ NOS: 5-12 added, substituted, or deleted.
More Like This:
Inventors:
TSUKAMOTO KENTARO (JP)
Application Number:
PCT/JP2023/008410
Publication Date:
September 07, 2023
Filing Date:
March 06, 2023
Export Citation:
Assignee:
FUJITA ACAD (JP)
International Classes:
C12N15/62; A61K38/16; A61P9/10; A61P43/00; C07K1/16; C07K14/195; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/31; C12N15/63; C12P21/02
Foreign References:
| JP2020132575A | 2020-08-31 |
Other References:
DATABASE Protein 21 July 2021 (2021-07-21), ANONYMOUS : "BafA family autotransporter [Bartonella koehlerae] ", XP093088429, retrieved from NCBI Database accession no. WP_034458933
KUMADAKI,KAYO ET AL.: "#Y-3 Comparison of the physiological activities of the BafA protein family produced by Bartonella bacteria", PREPRINTS OF THE 67TH JAPANESE SOCIETY FOR SYMPOSIUM ON TOXINS; SEPTEMBER 9, 2021 - SEPTEMBER 10, 2021, JAPANESE SOCIETY FOR SYMPOSIUM ON TOXINS, JP, vol. 67, 1 January 2021 (2021-01-01) - 10 September 2021 (2021-09-10), JP, pages 31 - 34, XP009549352, ISSN: 1344-9346
TSUKAMOTO KENTARO, SHINZAWA NAOAKI, KAWAI AKITO, SUZUKI MASAHIRO, KIDOYA HIROYASU, TAKAKURA NOBUYUKI, YAMAGUCHI HISATERU, KAMEYAMA: "The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis", NATURE COMMUNICATIONS, vol. 11, no. 1, XP093088436, DOI: 10.1038/s41467-020-17391-2
DATABASE Protein 29 June 2013 (2013-06-29), ANONYMOUS : "hypothetical protein, partial [Bartonella florencae] ", XP093088442, retrieved from NCBI Database accession no. WP_019219656
DATABASE Protein 202108004, ANONYMOUS : "BafA family autotransporter [Bartonella saheliensis] ", XP093088450, retrieved from NCBI Database accession no. WP_144752087
DATABASE Protein 21 July 2021 (2021-07-21), ANONYMOUS : "BafA family autotransporter [Bartonella rattimassiliensis] ", XP093088454, Database accession no. WP_026088004
JAFARI FARZANEH, KIANI-GHALEH FARID, EFTEKHARI SHAHRZAD, RAZZAGHSHOAR RAZLIGHI MEHDI, NAZARI NAZANIN, HAJIRAJABI MARYAM, MASOOMI S: "Cloning, overexpression, and structural characterization of a novel archaeal thermostable neopullulanase from Desulfurococcus mucosus DSM 2162", PREPARATIVE BIOCHEMISTRY AND BIOTECHNOLOGY, DEKKER, NEW YORK, NY, US, vol. 52, no. 10, 1 November 2022 (2022-11-01), US , pages 1190 - 1201, XP093088456, ISSN: 1082-6068, DOI: 10.1080/10826068.2022.2033996
BEN ELHOUL MOUNA; ZARAî JAOUADI NADIA; REKIK HATEM; OMRANE BENMRAD MAROUA; MECHRI SONDES; MOUJEHED EMNA; KOURDALI SIDALI; EL : "Biochemical and molecular characterization of new keratinoytic protease fromActinomadura viridiluteaDZ50", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ELSEVIER BV, NL, vol. 92, 4 July 2016 (2016-07-04), NL , pages 299 - 315, XP029755248, ISSN: 0141-8130, DOI: 10.1016/j.ijbiomac.2016.07.009
OMRANE BENMRAD MAROUA; MOUJEHED EMNA; BEN ELHOUL MOUNA; ZARAI JAOUADI NADIA; MECHRI SONDES; REKIK HATEM; KOURDALI SIDALI; EL HATTA: "A novel organic solvent- and detergent-stable serine alkaline protease fromTrametes cingulatastrain CTM10101", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ELSEVIER BV, NL, vol. 91, 10 June 2016 (2016-06-10), NL , pages 961 - 972, XP029680429, ISSN: 0141-8130, DOI: 10.1016/j.ijbiomac.2016.06.025
KUMADAKI,KAYO ET AL.: "#Y-3 Comparison of the physiological activities of the BafA protein family produced by Bartonella bacteria", PREPRINTS OF THE 67TH JAPANESE SOCIETY FOR SYMPOSIUM ON TOXINS; SEPTEMBER 9, 2021 - SEPTEMBER 10, 2021, JAPANESE SOCIETY FOR SYMPOSIUM ON TOXINS, JP, vol. 67, 1 January 2021 (2021-01-01) - 10 September 2021 (2021-09-10), JP, pages 31 - 34, XP009549352, ISSN: 1344-9346
TSUKAMOTO KENTARO, SHINZAWA NAOAKI, KAWAI AKITO, SUZUKI MASAHIRO, KIDOYA HIROYASU, TAKAKURA NOBUYUKI, YAMAGUCHI HISATERU, KAMEYAMA: "The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis", NATURE COMMUNICATIONS, vol. 11, no. 1, XP093088436, DOI: 10.1038/s41467-020-17391-2
DATABASE Protein 29 June 2013 (2013-06-29), ANONYMOUS : "hypothetical protein, partial [Bartonella florencae] ", XP093088442, retrieved from NCBI Database accession no. WP_019219656
DATABASE Protein 202108004, ANONYMOUS : "BafA family autotransporter [Bartonella saheliensis] ", XP093088450, retrieved from NCBI Database accession no. WP_144752087
DATABASE Protein 21 July 2021 (2021-07-21), ANONYMOUS : "BafA family autotransporter [Bartonella rattimassiliensis] ", XP093088454, Database accession no. WP_026088004
JAFARI FARZANEH, KIANI-GHALEH FARID, EFTEKHARI SHAHRZAD, RAZZAGHSHOAR RAZLIGHI MEHDI, NAZARI NAZANIN, HAJIRAJABI MARYAM, MASOOMI S: "Cloning, overexpression, and structural characterization of a novel archaeal thermostable neopullulanase from Desulfurococcus mucosus DSM 2162", PREPARATIVE BIOCHEMISTRY AND BIOTECHNOLOGY, DEKKER, NEW YORK, NY, US, vol. 52, no. 10, 1 November 2022 (2022-11-01), US , pages 1190 - 1201, XP093088456, ISSN: 1082-6068, DOI: 10.1080/10826068.2022.2033996
BEN ELHOUL MOUNA; ZARAî JAOUADI NADIA; REKIK HATEM; OMRANE BENMRAD MAROUA; MECHRI SONDES; MOUJEHED EMNA; KOURDALI SIDALI; EL : "Biochemical and molecular characterization of new keratinoytic protease fromActinomadura viridiluteaDZ50", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ELSEVIER BV, NL, vol. 92, 4 July 2016 (2016-07-04), NL , pages 299 - 315, XP029755248, ISSN: 0141-8130, DOI: 10.1016/j.ijbiomac.2016.07.009
OMRANE BENMRAD MAROUA; MOUJEHED EMNA; BEN ELHOUL MOUNA; ZARAI JAOUADI NADIA; MECHRI SONDES; REKIK HATEM; KOURDALI SIDALI; EL HATTA: "A novel organic solvent- and detergent-stable serine alkaline protease fromTrametes cingulatastrain CTM10101", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ELSEVIER BV, NL, vol. 91, 10 June 2016 (2016-06-10), NL , pages 961 - 972, XP029680429, ISSN: 0141-8130, DOI: 10.1016/j.ijbiomac.2016.06.025
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
Download PDF: