Title:
PERIODONTITIS TEST KIT USING MIRNA AS MARKER, AND TEST METHOD
Document Type and Number:
WIPO Patent Application WO/2017/195268
Kind Code:
A1
Abstract:
Since a miRNA that serves as a diagnostic marker for periodontitis of the present invention displays a change specific to periodontitis, diagnosis of periodontitis can be performed accurately.
Inventors:
OHSHIMA MITSUHIRO (JP)
YAMAGUCHI YOKO (JP)
HORIE MASAFUMI (JP)
SAITO AKIRA (JP)
NAGASE TAKAHIDE (JP)
IWAMOTO HISAMI (JP)
YAMAGUCHI YOKO (JP)
HORIE MASAFUMI (JP)
SAITO AKIRA (JP)
NAGASE TAKAHIDE (JP)
IWAMOTO HISAMI (JP)
Application Number:
PCT/JP2016/063846
Publication Date:
November 16, 2017
Filing Date:
May 10, 2016
Export Citation:
Assignee:
I C ELECTRONICS CO LTD (JP)
UNIV NIHON (JP)
UNIV TOKYO (JP)
UNIV NIHON (JP)
UNIV TOKYO (JP)
International Classes:
C12Q1/68; C12N15/09; G01N33/53
Foreign References:
| JP2008206483A | 2008-09-11 | |||
| JP2010256190A | 2010-11-11 | |||
| JP2004129584A | 2004-04-30 |
Other References:
OGATA, Y. ET AL.: "MicroRNA expression in inflamed and noninflamed gingival tissues from Japanese patients", J. ORAL SCI., vol. 56, no. 4, December 2014 (2014-12-01), pages 253 - 260, XP055600293, ISSN: 1343-4934, DOI: 10.2334/josnusd.56.253
XIE, Y.F. ET AL.: "Comparison of microRNA profiles of human periodontal diseased and healthy gingival tissues", INT. J. ORAL SCI., vol. 3, no. 3, July 2011 (2011-07-01), pages 125 - 134, XP055600295, ISSN: 1674-2818, DOI: 10.4248/IJOS11046
STOECKLIN-WASMER, C. ET AL.: "MicroRNAs and their target genes in gingival tissues", J. DENT. RES., vol. 91, no. 10, October 2012 (2012-10-01), pages 934 - 940, XP055532400, ISSN: 0022-0345, DOI: doi:10.1177/0022034512456551
PERRI, R. ET AL.: "MicroRNA modulation in obesity and periodontitis", J. DENT. RES., vol. 91, no. 1, January 2012 (2012-01-01), pages 33 - 38, XP055484845, ISSN: 0022-0345, DOI: doi:10.1177/0022034511425045
XIE, Y.F. ET AL.: "Comparison of microRNA profiles of human periodontal diseased and healthy gingival tissues", INT. J. ORAL SCI., vol. 3, no. 3, July 2011 (2011-07-01), pages 125 - 134, XP055600295, ISSN: 1674-2818, DOI: 10.4248/IJOS11046
STOECKLIN-WASMER, C. ET AL.: "MicroRNAs and their target genes in gingival tissues", J. DENT. RES., vol. 91, no. 10, October 2012 (2012-10-01), pages 934 - 940, XP055532400, ISSN: 0022-0345, DOI: doi:10.1177/0022034512456551
PERRI, R. ET AL.: "MicroRNA modulation in obesity and periodontitis", J. DENT. RES., vol. 91, no. 1, January 2012 (2012-01-01), pages 33 - 38, XP055484845, ISSN: 0022-0345, DOI: doi:10.1177/0022034511425045
Attorney, Agent or Firm:
SHIRAKATA Yumiko (JP)
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