Title:
PHARMACEUTICAL COMPOSITION COMPRISING LIPASE INHIBITOR FOR TREATMENT OR TREATMENT OF RNA VIRAL INFECTIONS
Document Type and Number:
WIPO Patent Application WO/2022/270978
Kind Code:
A1
Abstract:
The present invention relates to a therapeutic agent of a lipase inhibitor for a wide spectrum of RNA viral infections in humans and animals. More specifically, the lipase inhibitor can be used as a therapeutic agent for influenza A virus infection, bovine coronavirus infection, porcine epidemic diarrhea coronavirus infection, bovine rotavirus infection, porcine reproductive and respiratory syndrome virus infection, and sapoviral infection and furthermore, can be utilized as a therapeutic agent for various RNA viral infections in humans and animals, such as infections with SARS CoV-1, MERS-CoV, Zika virus, dengue fever virus, and hepatitis A and C viruses.
Inventors:
CHO KYOUNG OH (KR)
JEON TAE IL (KR)
LEE SUN WOO (KR)
BAEK YEONG BIN (KR)
KWON HYUNG JUN (KR)
CHOI HUENG SIK (KR)
PARK SANG IK (KR)
SHARIF MUHAMMAD (KR)
LIM JEONG AH (KR)
JEON TAE IL (KR)
LEE SUN WOO (KR)
BAEK YEONG BIN (KR)
KWON HYUNG JUN (KR)
CHOI HUENG SIK (KR)
PARK SANG IK (KR)
SHARIF MUHAMMAD (KR)
LIM JEONG AH (KR)
Application Number:
PCT/KR2022/009041
Publication Date:
December 29, 2022
Filing Date:
June 24, 2022
Export Citation:
Assignee:
UNIV NAT CHONNAM IND FOUND (KR)
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
A61K31/17; A61K31/402; A61K31/4245; A61K31/5375; A61P31/14
Foreign References:
| KR20140040676A | 2014-04-03 | |||
| US9206115B2 | 2015-12-08 | |||
| US20180256623A1 | 2018-09-13 | |||
| KR20210083385A | 2021-07-06 | |||
| KR20220077063A | 2022-06-08 |
Other References:
LAUFMAN ORLY; PERRINO JOHN; ANDINO RAUL: "Viral Generated Inter-Organelle Contacts Redirect Lipid Flux for Genome Replication", CELL, ELSEVIER, AMSTERDAM NL, vol. 178, no. 2, 13 June 2019 (2019-06-13), Amsterdam NL , pages 275, XP085739926, ISSN: 0092-8674, DOI: 10.1016/j.cell.2019.05.030
LI XINHONG, WANG MINGSHU, CHENG ANCHUN, WEN XINGJIAN, OU XUMIN, MAO SAI, GAO QUN, SUN DI, JIA RENYONG, YANG QIAO, WU YING, ZHU DEK: "Enterovirus Replication Organelles and Inhibitors of Their Formation", FRONTIERS IN MICROBIOLOGY, vol. 11, XP093017255, DOI: 10.3389/fmicb.2020.01817
no. 1469924-27-3
LI XINHONG, WANG MINGSHU, CHENG ANCHUN, WEN XINGJIAN, OU XUMIN, MAO SAI, GAO QUN, SUN DI, JIA RENYONG, YANG QIAO, WU YING, ZHU DEK: "Enterovirus Replication Organelles and Inhibitors of Their Formation", FRONTIERS IN MICROBIOLOGY, vol. 11, XP093017255, DOI: 10.3389/fmicb.2020.01817
no. 1469924-27-3
Attorney, Agent or Firm:
YOON, Dae Woong (KR)
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