Title:
PHARMACEUTICAL COMPOSITION CONTAINING GLY-THYMOSIN β4 (GLY-Tβ4) FOR TREATMENT OF DRY EYE
Document Type and Number:
WIPO Patent Application WO/2018/230858
Kind Code:
A2
Abstract:
The present invention relates to a pharmaceutical composition containing Gly-Tβ4 as an active ingredient for the treatment of dry eye, wherein the pharmaceutical composition restores damaged corneal epithelial cells while showing an effect of proliferating goblet cells, and thus is effective in the treatment, prevention, and alleviation of dry eye.
Inventors:
JANG KYOUNG HWA (KR)
KANG SEOK CHAN (KR)
JANG DO SOO (KR)
KIM YOUNG MOK (KR)
KIM WANSEOP PAUL (KR)
UM KEY AN (KR)
KANG SEOK CHAN (KR)
JANG DO SOO (KR)
KIM YOUNG MOK (KR)
KIM WANSEOP PAUL (KR)
UM KEY AN (KR)
Application Number:
PCT/KR2018/006030
Publication Date:
December 20, 2018
Filing Date:
May 28, 2018
Export Citation:
Assignee:
HUONS CO LTD (KR)
International Classes:
A61K38/16; A61K9/00; A61K9/08
Other References:
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 257, no. 2, 1982, pages 1000 - 1006
"Thymosin β4 activates integrin-linked kinases and enhances cardiac cell migration, survival, and heart repair", NATURE, vol. 432, 25 November 2004 (2004-11-25)
See also references of EP 3639842A4
"Thymosin β4 activates integrin-linked kinases and enhances cardiac cell migration, survival, and heart repair", NATURE, vol. 432, 25 November 2004 (2004-11-25)
See also references of EP 3639842A4
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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