Title:
PHARMACEUTICAL COMPOSITION FOR INHALATION
Document Type and Number:
WIPO Patent Application WO/2013/175781
Kind Code:
A1
Abstract:
[Problem] To provide a novel powdery preparation for inhalation, which contains a benz[d][1,3]oxazine derivative as an active ingredient and has excellent inhalation properties. [Solution] A pharmaceutical composition having a dosage form of a powdery preparation for inhalation, which comprises carrier particles and crystals of a compound represented by formula (1) which are adhered onto the carrier particles, wherein, as the crystals of a compound represented by formula (1), crystals which have a characteristic peak at 8.4˚ in powder X-ray diffraction (diffraction angle: 2θ ± 0.5˚) are contained and crystals of a compound represented by formula (1) which have a characteristic peak at 7.7˚ in powder X-ray diffraction (diffraction angle: 2θ ± 0.5˚) are not substantially contained, and wherein the cumulative 10% particle diameter of the carrier particles is 20 μm or more.
Inventors:
USHIGOME SATORU (JP)
OOHASHI KATSUYA (JP)
MINAGAWA WATARU (JP)
TANAKA AKITSU (JP)
OOHASHI KATSUYA (JP)
MINAGAWA WATARU (JP)
TANAKA AKITSU (JP)
Application Number:
PCT/JP2013/003249
Publication Date:
November 28, 2013
Filing Date:
May 22, 2013
Export Citation:
Assignee:
KYORIN SEIYAKU KK (JP)
International Classes:
A61K31/536; A61K9/14; A61K9/62; A61K47/26; C07D413/14
Domestic Patent References:
| WO2011036895A1 | 2011-03-31 |
Foreign References:
| JP2003034652A | 2003-02-07 | |||
| JP2007534693A | 2007-11-29 | |||
| JP2010533697A | 2010-10-28 | |||
| JP2001072586A | 2001-03-21 | |||
| JPH08501056A | 1996-02-06 |
Attorney, Agent or Firm:
MIZUNO, Katsufumi et al. (JP)
Katsufumi Mizuno (JP)
Katsufumi Mizuno (JP)
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