Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING VASCULAR DISEASES, COMPRISING PIPERLONGUMINE-BASED COMPOUND AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2023/055020
Kind Code:
A1
Abstract:
The present invention relates to use of a piperlongumine-based compound for treating vascular diseases. Particularly, the piperlongumine-based compound according to the present invention promotes the expression of HO-1 protein and, simultaneously, inhibits the expression of MCP-1 protein, and thus can be effectively used in the treatment of vascular diseases such as arteriosclerosis.
More Like This:
Inventors:
JOO SEONG SOO (KR)
Application Number:
PCT/KR2022/014420
Publication Date:
April 06, 2023
Filing Date:
September 27, 2022
Export Citation:
Assignee:
JOO SEONG SOO (KR)
International Classes:
A61K31/4412; A23L33/10; A61K31/24; A61K31/4015; A61K31/4439; A61K31/45; A61K31/495; A61P9/00; A61P9/10; A61P27/02
Foreign References:
| JPH02225458A | 1990-09-07 | |||
| JPH07179338A | 1995-07-18 | |||
| KR101468752B1 | 2014-12-03 |
Other References:
NAGASAKA TATSUO, MOMOSE KENICHI, HAMAGUCHI FUMIKO, YAMADA KENJI, YAMADA HIROAKI, SUZUKI YOSHIKUNI: "Synthesis of 1-trans-Cinnamoyl- and 1-[trans-3-(Pyridyl)acryloyl]-2-pyrrolidinone Derivatives and Their Effect on Hemicholinium-Induced Impairment of Water Maze Learning in Mice", YAKUGAKU ZASSHI : JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, PHARMACEUTICAL SOCIETY OF JAPAN, vol. 112, no. 2, 1 January 1992 (1992-01-01), pages 100 - 107, XP055902562, ISSN: 0031-6903, DOI: 10.1248/yakushi1947.112.2_100
SHI JINGSONG, JIANG SONG, QIU DANDAN, LE WEIBO, WANG XIAO, LU YINHUI, LIU ZHIHONG: "Rapid Identification of Potential Drugs for Diabetic Nephropathy Using Whole-Genome Expression Profiles of Glomeruli", BIOMED RESEARCH INTERNATIONAL, HINDAWI PUBLISHING CORPORATION, vol. 2016, 1 January 2016 (2016-01-01), pages 1 - 13, XP093054311, ISSN: 2314-6133, DOI: 10.1155/2016/1634730
SHI JINGSONG, JIANG SONG, QIU DANDAN, LE WEIBO, WANG XIAO, LU YINHUI, LIU ZHIHONG: "Rapid Identification of Potential Drugs for Diabetic Nephropathy Using Whole-Genome Expression Profiles of Glomeruli", BIOMED RESEARCH INTERNATIONAL, HINDAWI PUBLISHING CORPORATION, vol. 2016, 1 January 2016 (2016-01-01), pages 1 - 13, XP093054311, ISSN: 2314-6133, DOI: 10.1155/2016/1634730
Attorney, Agent or Firm:
WETHEPEOPLE IP & LAW FIRM (KR)
Download PDF:
Previous Patent: METHOD FOR PROVIDING DART GAME IMAGE
Next Patent: METHOD FOR MANUFACTURING POLARIZING PLATE
Next Patent: METHOD FOR MANUFACTURING POLARIZING PLATE