Title:
PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER
Document Type and Number:
WIPO Patent Application WO/2023/013719
Kind Code:
A1
Abstract:
There has been demand to identify miRNA that could be made to be involved in treatment and/or prevention in common across various cancer types from a variety of miRNA relating to cancer, and to provide a novel pharmaceutical composition for treating and/or preventing cancer in which a polynucleotide derived from said miRNA is employed as an active ingredient. The present invention provides an agent for treating and/or preventing cancer, said agent containing, as an active ingredient, a polynucleotide including a base sequence represented by SEQ ID NO: 1.
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Inventors:
KASHIMURA CHIORI (JP)
MIYANO ATSUKO (JP)
TAKAYAMA AIKO (JP)
TAKAHASHI KEI (JP)
MIYANO ATSUKO (JP)
TAKAYAMA AIKO (JP)
TAKAHASHI KEI (JP)
Application Number:
PCT/JP2022/029888
Publication Date:
February 09, 2023
Filing Date:
August 04, 2022
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K31/7088; A61K35/76; A61K45/00; A61K48/00; A61P35/00; A61P35/02; A61P43/00; C12N15/113
Domestic Patent References:
| WO2005095613A1 | 2005-10-13 |
Foreign References:
| JP2011507534A | 2011-03-10 | |||
| JP2016064989A | 2016-04-28 | |||
| CN110564729A | 2019-12-13 | |||
| CN102140469A | 2011-08-03 |
Other References:
FUJITA, YU ET AL.: "The Clinical Relevance of the miR-197/ CKSlB/STAT3-mediated PD- L1 Network in Chemoresistant Non-small- cell Lung Cancer", MOLECULAR THERAPY, vol. 23, no. 4, 2015, pages 717 - 727, XP055517736, DOI: 10.1038/mt.2015.10
LI HONGBIN, JIN XIAODONG, LIU BINGTAO, ZHANG PENGCHENG, CHEN WEIQIANG, LI QIANG: "CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer", BMC CANCER, vol. 19, no. 1, 1 December 2019 (2019-12-01), XP093033687, DOI: 10.1186/s12885-019-6017-2
SUDO KAZUKI, KATO KEN, MATSUZAKI JUNTARO, TAKIZAWA SATOKO, AOKI YOSHIAKI, SHOJI HIROKAZU, IWASA SATORU, HONMA YOSHITAKA, TAKASHIMA: "Identification of serum microRNAs predicting the response of esophageal squamous-cell carcinoma to nivolumab", JAPANESE JOURNAL OF CLINICAL ONCOLOGY, vol. 50, no. 50, 1 January 2020 (2020-01-01), pages 114 - 121, XP093033688, DOI: 10.1093/jjco/hyz146
ZHAO, MAOJIA ET AL.: "Drosha-independent miR-6778-5p strengthens gastric cancer stem cell sternness via regulation of cytosolic one-carbon folate metabolism", CANCER LETTERS, vol. 478, 2020, pages 8 - 21, XP086113064, DOI: 10.1016/j.canlet.2020.02.040
LI HONGBIN, JIN XIAODONG, LIU BINGTAO, ZHANG PENGCHENG, CHEN WEIQIANG, LI QIANG: "CircRNA CBL.11 suppresses cell proliferation by sponging miR-6778-5p in colorectal cancer", BMC CANCER, vol. 19, no. 1, 1 December 2019 (2019-12-01), XP093033687, DOI: 10.1186/s12885-019-6017-2
SUDO KAZUKI, KATO KEN, MATSUZAKI JUNTARO, TAKIZAWA SATOKO, AOKI YOSHIAKI, SHOJI HIROKAZU, IWASA SATORU, HONMA YOSHITAKA, TAKASHIMA: "Identification of serum microRNAs predicting the response of esophageal squamous-cell carcinoma to nivolumab", JAPANESE JOURNAL OF CLINICAL ONCOLOGY, vol. 50, no. 50, 1 January 2020 (2020-01-01), pages 114 - 121, XP093033688, DOI: 10.1093/jjco/hyz146
ZHAO, MAOJIA ET AL.: "Drosha-independent miR-6778-5p strengthens gastric cancer stem cell sternness via regulation of cytosolic one-carbon folate metabolism", CANCER LETTERS, vol. 478, 2020, pages 8 - 21, XP086113064, DOI: 10.1016/j.canlet.2020.02.040
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