Title:
PHARMACEUTICAL COMPOSITIONS COMPRISING A 7-(2-AMINOETHYL)-BENZOTHIAZOLONE AND A PDE4 INHIBITOR
Document Type and Number:
WIPO Patent Application WO2001011933
Kind Code:
A3
Abstract:
The present invention provides a pharmaceutical composition, pharmaceutical product or kit comprising a first active ingredient (A) being 4-hydroxy-7-[2-[2-[3-[2-phenylethoxy]propylsulphonyl]ethylamino]ethyl]-1,3-benzothiazol-2(3H)-one or a pharmaceutically acceptable salt thereof, and a second active ingredient (B) being a PDE4 inhibitor, for use in the treatment of obstructive airways diseases.
Inventors:
INCE FRANCIS (GB)
DIXON JOHN (GB)
HOLT PHILIP (GB)
DIXON JOHN (GB)
HOLT PHILIP (GB)
Application Number:
PCT/GB2000/003114
Publication Date:
June 14, 2001
Filing Date:
August 14, 2000
Export Citation:
Assignee:
ASTRAZENECA UK LTD (SE)
INCE FRANCIS (GB)
DIXON JOHN (GB)
HOLT PHILIP (GB)
INCE FRANCIS (GB)
DIXON JOHN (GB)
HOLT PHILIP (GB)
International Classes:
A61K31/43; A61K31/44; A61K31/445; A61K31/47; A61K31/50; A61K31/505; A61K31/52; (IPC1-7): A61K31/52; A61K31/275; A61K31/40; A61K31/415; A61K31/44; A61K31/47; A61K31/50; A61K31/505; A61P11/00
Domestic Patent References:
| WO1993024473A1 | 1993-12-09 |
Other References:
"A heterogeneous collection of novel phosphodiesterase Type 4 inhibitors.", EXPERT OPINION ON THERAPEUTIC PATENTS, (1998) 8/11 (1529-1535)., XP000986458
SILVESTRE, J. ET AL: "SB-207499. antiasthmatic/antiinflammatory, phosphodiesterase IV inhibitor", DRUGS FUTURE (1998), 23(6), 607-615, 1998, XP000981875
BARNES P.J.: "New therapies for chronic obstructive pulmonary disease.", THORAX, (1998) 53/2 (137-147)., XP000986442
SKORODIN M.S.: "Pharmacotherapy for asthma and chronic obstructive pulmonary disease: Current thinking, practices, and controversies.", ARCHIVES OF INTERNAL MEDICINE, (1993) 153/7 (814-824)., XP000986471
IKEDA A. ET AL: "Pharmacological treatment in acute exacerbations of chronic obstructive pulmonary disease.", DRUGS AND AGING, (1998) 12/2 (129-137)., XP000986468
LURIE A. ET AL: "Long-term management of reversible obstructive airways disease in adults.", LUNG, (1990) 168/SUPPL. (154-167)., XP000986437
SILVESTRE, J. ET AL: "SB-207499. antiasthmatic/antiinflammatory, phosphodiesterase IV inhibitor", DRUGS FUTURE (1998), 23(6), 607-615, 1998, XP000981875
BARNES P.J.: "New therapies for chronic obstructive pulmonary disease.", THORAX, (1998) 53/2 (137-147)., XP000986442
SKORODIN M.S.: "Pharmacotherapy for asthma and chronic obstructive pulmonary disease: Current thinking, practices, and controversies.", ARCHIVES OF INTERNAL MEDICINE, (1993) 153/7 (814-824)., XP000986471
IKEDA A. ET AL: "Pharmacological treatment in acute exacerbations of chronic obstructive pulmonary disease.", DRUGS AND AGING, (1998) 12/2 (129-137)., XP000986468
LURIE A. ET AL: "Long-term management of reversible obstructive airways disease in adults.", LUNG, (1990) 168/SUPPL. (154-167)., XP000986437
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