Title:
PHENOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2005/095429
Kind Code:
A1
Abstract:
A phenol derivative represented by the following general formula (I), a pharmacologically acceptable salt of the derivative, or a prodrug of either. They have human SGLT inhibitory activity and are useful as a preventive or therapeutic agent for diseases attributable to hyperglycemia, such as diabetes, postprandial hyperglycemia, impaired glucose tolerance, complications of diabetes, and obesity. In the chemical structural formula, R1 and R2 each represents H, OH, NH2, etc.; R3 and R4 each represents H, OH, halogeno, optionally substituted alkyl, etc.; ring A represents aryl or heteroaryl; and G represents a group represented by the following general formula (G), wherein E1 represents H or F and E2 represents H, F, methyl, etc.
More Like This:
| JP2010500290 | Compositions and methods for regulating JNK protein |
| JP2008074742 | INHIBITOR FOR BLOOD SUGAR ELEVATION |
| WO/2017/040588 | COMPOSITION FOR TREATING AND PREVENTING VIRAL INFECTIONS |
Inventors:
FUJIKURA HIDEKI (JP)
FUSHIMI NOBUHIKO (JP)
ISAJI MASAYUKI (JP)
FUSHIMI NOBUHIKO (JP)
ISAJI MASAYUKI (JP)
Application Number:
PCT/JP2005/006702
Publication Date:
October 13, 2005
Filing Date:
March 30, 2005
Export Citation:
Assignee:
KISSEI PHARMACEUTICAL (JP)
FUJIKURA HIDEKI (JP)
FUSHIMI NOBUHIKO (JP)
ISAJI MASAYUKI (JP)
FUJIKURA HIDEKI (JP)
FUSHIMI NOBUHIKO (JP)
ISAJI MASAYUKI (JP)
International Classes:
A61K31/7034; A61P3/10; C07H15/203; (IPC1-7): C07H15/203; A61K31/7034; A61P3/10
Domestic Patent References:
| WO2001068660A1 | 2001-09-20 |
Foreign References:
| JP2004500416A | 2004-01-08 |
Other References:
See also references of EP 1731524A4
Download PDF: