Title:
PLASMODIUM FALCIPARUM ANTIGENS AND VACCINE AND DIAGNOSTIC USES THEREOF
Document Type and Number:
WIPO Patent Application WO2002092628
Kind Code:
A3
Abstract:
The invention concerns novel Plasmodium falciparum antigens and their vaccine and diagnostic applications. More particularly, the invention concerns immunogenic polynucleotide and polypeptide molecules, compositions comprising them, and methods for diagnosis and vaccination of malaria.
Inventors:
DRUILHE PIERRE (FR)
GRUENER ANNE-CHARLOTTE (FR)
GRUENER ANNE-CHARLOTTE (FR)
Application Number:
PCT/FR2002/001637
Publication Date:
September 25, 2003
Filing Date:
May 15, 2002
Export Citation:
Assignee:
PASTEUR INSTITUT (FR)
DRUILHE PIERRE (FR)
GRUENER ANNE-CHARLOTTE (FR)
DRUILHE PIERRE (FR)
GRUENER ANNE-CHARLOTTE (FR)
International Classes:
A61P33/06; C07K14/445; C12N15/30; A61K39/00; (IPC1-7): C07K14/445; C12N15/30; A61K39/00; G01N33/53; G01N33/569; C07K16/20; C12Q1/00; C12N15/11; A61P33/06
Domestic Patent References:
| WO2000025728A2 | 2000-05-11 |
Foreign References:
| US6191270B1 | 2001-02-20 |
Other References:
DAUBERSIES PIERRE ET AL: "Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3", NATURE MEDICINE, NATURE AMERICA, NEW YORK, US, vol. 6, no. 11, November 2000 (2000-11-01), pages 1258 - 1263, XP002213662, ISSN: 1078-8956
BENMOHAMED L ET AL: "High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 18, no. 25, June 2000 (2000-06-01), pages 2843 - 2855, XP004203575, ISSN: 0264-410X
GARDNER M J ET AL: "CHROMOSOME 2 SEQUENCE OF THE HUMAN MALARIA PARASITE PLASMODIUM FALCIPARUM", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 282, 6 November 1998 (1998-11-06), pages 1126 - 1132, XP002907181, ISSN: 0036-8075
DATABASE EMBL [online] 22 December 2001 (2001-12-22), XP002222215, Database accession no. BM273600
BENMOHAMED L ET AL: "High immunogenicity in chimpanzees of peptides and lipopeptides derived from four new Plasmodium falciparum pre-erythrocytic molecules", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 18, no. 25, June 2000 (2000-06-01), pages 2843 - 2855, XP004203575, ISSN: 0264-410X
GARDNER M J ET AL: "CHROMOSOME 2 SEQUENCE OF THE HUMAN MALARIA PARASITE PLASMODIUM FALCIPARUM", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 282, 6 November 1998 (1998-11-06), pages 1126 - 1132, XP002907181, ISSN: 0036-8075
DATABASE EMBL [online] 22 December 2001 (2001-12-22), XP002222215, Database accession no. BM273600
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