Title:
PLX3397 HYDROCHLORIDE CRYSTAL FORM, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/215521
Kind Code:
A1
Abstract:
The present invention relates to a PLX3397 hydrochloride crystal form, a preparation method therefor and use thereof. The PLX3397 hydrochloride crystal form has higher solubility, larger particle size, and good stability, especially better mechanical stability, is favorable for separation of products in subsequent production, provides a better choice for preparing PLX3397-containing pharmaceutical preparations, and is very important to medicinal development.
Inventors:
CHEN MINHUA (CN)
ZHANG YANFENG (CN)
ZOU PO (CN)
ZHANG XIAOYU (CN)
ZHANG YANFENG (CN)
ZOU PO (CN)
ZHANG XIAOYU (CN)
Application Number:
PCT/CN2017/087711
Publication Date:
December 21, 2017
Filing Date:
June 09, 2017
Export Citation:
Assignee:
CRYSTAL PHARMACEUTICAL (SUZHOU) CO LTD (CN)
International Classes:
C07D471/04; A61K31/444; A61P35/00
Domestic Patent References:
| WO2016179412A1 | 2016-11-10 |
Foreign References:
| CN103497188A | 2014-01-08 | |||
| CN101605787A | 2009-12-16 |
Other References:
See also references of EP 3461823A4
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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