Title:
POPULATION BASED ASSESSMENTS AND MEANS TO RANK THE RELATIVE IMMUNOGENICITY OF PROTEINS
Document Type and Number:
WIPO Patent Application WO2003073068
Kind Code:
A3
Abstract:
The present invention provides means to assess immune response profiles of populations. In particular, the present invention provides means to qualitatively assess the immune response of human populations wherein the immune response directed against any protein of interest is analyzed. The present invention further provides means to rank proteins based on their relative immunogenicity. In addition, the present invention provides means to create proteins with reduced immunogenicity for use in various applications.
Inventors:
HARDING FIONA A (US)
Application Number:
PCT/US2003/005670
Publication Date:
December 11, 2003
Filing Date:
February 26, 2003
Export Citation:
Assignee:
GENENCOR INT (US)
HARDING FIONA A (US)
HARDING FIONA A (US)
International Classes:
G01N33/53; C12N9/56; C12Q1/02; G01N33/50; G01N33/566; G01N33/567; (IPC1-7): G01N33/53; G01N33/567; C12N5/06
Foreign References:
| US5691147A | 1997-11-25 | |||
| US6451316B1 | 2002-09-17 | |||
| US6110695A | 2000-08-29 | |||
| US5627025A | 1997-05-06 |
Other References:
See also references of EP 1483581A4
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