Title:
RNA DETECTION ENZYMES
Document Type and Number:
WIPO Patent Application WO2003073067
Kind Code:
A3
Abstract:
The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5' nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
Inventors:
MA WUPO (US)
LYAMICHEV VICTOR (US)
KAISER MICHAEL (US)
LYAMICHEV NATALIE E (US)
ALLAWI HATIM TAYSIR (US)
SCHAEFER JAMES J (US)
NERI BRUCE N (US)
LUKOWIAK ANDREW A (US)
LYAMICHEV VICTOR (US)
KAISER MICHAEL (US)
LYAMICHEV NATALIE E (US)
ALLAWI HATIM TAYSIR (US)
SCHAEFER JAMES J (US)
NERI BRUCE N (US)
LUKOWIAK ANDREW A (US)
Application Number:
PCT/US2003/005613
Publication Date:
November 18, 2004
Filing Date:
February 26, 2003
Export Citation:
Assignee:
THIRD WAVE TECHNOLOGIES (US)
MA WUPO (US)
LYAMICHEV VICTOR (US)
KAISER MICHAEL (US)
LYAMICHEV NATALIE E (US)
ALLAWI HATIM TAYSIR (US)
SCHAEFER JAMES J (US)
NERI BRUCE N (US)
LUKOWIAK ANDREW A (US)
MA WUPO (US)
LYAMICHEV VICTOR (US)
KAISER MICHAEL (US)
LYAMICHEV NATALIE E (US)
ALLAWI HATIM TAYSIR (US)
SCHAEFER JAMES J (US)
NERI BRUCE N (US)
LUKOWIAK ANDREW A (US)
International Classes:
C12N1/15; C12N1/19; C12N15/09; C12N1/21; C12N5/10; C12N9/12; C12N9/16; C12N9/22; C12Q1/68; H04L29/06; H04L29/08; (IPC1-7): C12N9/22; C12P19/34
Domestic Patent References:
| WO2001090337A2 | 2001-11-29 |
Other References:
See also references of EP 1504093A4
Download PDF: