PREVENTION OR REMEDIATION COMPOSITION FOR DEMENTIA OR DEPRESSION

Title:

PREVENTION OR REMEDIATION COMPOSITION FOR DEMENTIA OR DEPRESSION

Document Type and Number:

WIPO Patent Application WO/2018/047980

Kind Code:

A1

Abstract:

The present invention provides a prevention or remediation composition for dementia or depression, having a more effective prevention or remediation effect against dementia or depression, in particular against depression caused by stress, whereof the safety is high, and can be ingested or administered continuously. The composition contains 35% by mole or more of leucine relative to the total content in essential amino acids, and one or more species of essential amino acids other than leucine.

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Inventors:

NISHITANI SHINOBU (JP)

Application Number:

PCT/JP2017/033174

Publication Date:

March 15, 2018

Filing Date:

September 08, 2017

Export Citation:

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Assignee:

AJINOMOTO KK (JP)

International Classes:

A61K31/198; A61P25/28

Domestic Patent References:

WO2013073644A1	2013-05-23
WO2008044691A1	2008-04-17

Foreign References:

JP2004292437A	2004-10-21
EP2959895A1	2015-12-30
JP2009126830A	2009-06-11
US20070286909A1	2007-12-13
JP2009511576A	2009-03-19

Other References:

RUNGTIP, SOI-AMPORNKUL ET AL.: "Protective effects of pre-germinated brown rice extract against amyloid beta-peptide (1-42)-induced apoptosis in neuronal SK -N-SH cells", ALZHEIMER'S AND DEMENTIA, vol. 7, no. 4, July 2011 (2011-07-01), pages 117, XP055473974, DOI: doi:10.1016/j.jalz.2011.05.297
RAVAGLIA, GIOVANNI ET AL.: "Plasma amino acid concentrations in healthy and cognitively impaired oldest-old individuals: associations with anthropometric parameters of body composition and functional disability", BR J NUTR, vol. 88, no. 5, November 2002 (2002-11-01), pages 563 - 572, XP055473975, DOI: doi:10.1079/BJN2002700
See also references of EP 3510999A4

Attorney, Agent or Firm:

TAKASHIMA, Hajime et al. (JP)

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