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Title:
PREVENTION AND/OR TREATMENT OF A DISEASE ASSOCIATED WITH STAT3
Document Type and Number:
WIPO Patent Application WO/2022/022524
Kind Code:
A1
Abstract:
Provided are prevention and/or treatment of a disease associated with STAT3 by regulation of 14-3-3 σ.

Inventors:
LIU CHAOHONG (CN)
Application Number:
PCT/CN2021/108721
Publication Date:
February 03, 2022
Filing Date:
July 27, 2021
Export Citation:
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Assignee:
HUAZHONG UNIV OF SCIENCE & TECHNOLOGY (CN)
International Classes:
A61K38/16; A61P37/00; C07K14/00
Domestic Patent References:
WO2019204614A12019-10-24
Foreign References:
CN103608010A2014-02-26
Other References:
PAN,W.N.ET AL.: "New understanding of 14-3-3 proteins", BEIJING BIOMEDICAL ENGINEERING, vol. 34, no. 3, 30 June 2015 (2015-06-30), pages 320 - 325, XP009533539, ISSN: 1002-3208
WANG B, ET AL.: "ISOLATION OF HIGH-AFFINITY PEPTIDE ANTAGONISTS OF 14-3-3 PROTEINS BY PHAGE DISPLAY", BIOCHEMISTRY, vol. 38, no. 38, 21 September 1999 (1999-09-21), pages 12499 - 12504, XP001094762, ISSN: 0006-2960, DOI: 10.1021/bi991353h
MASTERS SHANE C ET AL: "14-3-3 proteins mediate an essential anti-apoptotic signal.", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 276, no. 48, 30 November 2001 (2001-11-30), US , pages 45193 - 45200, XP002209344, ISSN: 0021-9258, DOI: 10.1074/jbc.M105971200
PAN,W.N.ET AL.: "14-3-3 Is Involved in ERK1/2 Signaling Pathway of Rat Vascular Smooth Muscle Cells Proliferation Induced by Apelin-13", PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, vol. 38, no. 12, 31 December 2011 (2011-12-31), pages 1153 - 1161, XP009533538
Attorney, Agent or Firm:
WU, FENG & ZHANG (CN)
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