Title:
PREVENTIVE OR THERAPEUTIC AGENT FOR NEURODEGENERATIVE DISEASE
Document Type and Number:
WIPO Patent Application WO/2023/190316
Kind Code:
A1
Abstract:
The present invention provides a preventive or therapeutic agent for neurodegenerative disease, the agent containing an agent for suppressing KLHL32 gene expression. The present invention also provides a screening method for a preventive or therapeutic agent for neurodegenerative disease, the method comprising: (1) a step for bringing a test substance into contact with cells that express the KLHL32 gene; and (2) a step for selecting, as a candidate for the preventive or therapeutic agent for neurodegenerative disease, a test substance which has caused a reduction in KLHL32 gene expression.
Inventors:
INOUE HARUHISA (JP)
KONDO TAKAYUKI (JP)
YAMAMOTO TAKUYA (JP)
YADA YUICHIRO (JP)
KONDO TAKAYUKI (JP)
YAMAMOTO TAKUYA (JP)
YADA YUICHIRO (JP)
Application Number:
PCT/JP2023/012161
Publication Date:
October 05, 2023
Filing Date:
March 27, 2023
Export Citation:
Assignee:
UNIV KYOTO (JP)
International Classes:
A61K45/00; A61K31/7088; A61K31/7105; A61K31/713; A61K48/00; A61P21/02; A61P25/00; A61P25/14; A61P25/16; A61P25/28; C07K14/47; C07K16/18; C12N5/074; C12N5/079; C12N5/10; C12N15/09; C12N15/113; C12N15/12; C12N15/13; C12Q1/02; C12Q1/6876; G01N33/15; G01N33/50; G01N33/53; G01N33/68
Domestic Patent References:
| WO2006138363A2 | 2006-12-28 |
Attorney, Agent or Firm:
MURAOKA, Koichiro et al. (JP)
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