Title:
PROCESS FOR ATTACHING EFFECTOR MOLECULES TO PROTEINS
Document Type and Number:
WIPO Patent Application WO2007003898
Kind Code:
A8
Abstract:
The present invention provides a process for attaching one or more effector molecules to one or more cysteines in a protein comprising: a) activating one or more cysteines in the protein by diafiltering the protein against a monothiol reducing agent or a multi-thiol reducing agent which is incapable of forming intramolecular disulphide bonds and b) reacting the treated protein with an effector molecule.
Inventors:
HEYWOOD SAM PHILIP (GB)
Application Number:
PCT/GB2006/002416
Publication Date:
October 09, 2008
Filing Date:
June 29, 2006
Export Citation:
Assignee:
UCB PHARMA SA (BE)
HEYWOOD SAM PHILIP (GB)
HEYWOOD SAM PHILIP (GB)
International Classes:
A61K39/395; A61K47/48
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