Title:
PROCESS FOR PRODUCING DIBENZOTHIAZEPINE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2001/004106
Kind Code:
A1
Abstract:
A process for producing dibenzothiazepine derivatives typified by dibenzo[b,f][1,4]thiazepin-11-one which are usable as the starting material for producing 11-[4-(2-(2-hydroxyethoxy)ethyl)]-1-piperazinyldibenzothiazepine derivatives useful as a psychotropic drug, which comprises reacting a nitrobenzene derivative with a thiosalicylic acid derivative, reducing the thus obtained 2-nitro-2'-carboxy-diphenylsulfide derivative, and then further dehydrating and condensing the thus obtained 2-amino-2'-carboxy-diphenylsulfide derivative.
Inventors:
HARADA KATSUMASA (JP)
NISHINO SHIGEYOSHI (JP)
YOSHII KIYOTAKA (JP)
NISHINO SHIGEYOSHI (JP)
YOSHII KIYOTAKA (JP)
Application Number:
PCT/JP1999/003719
Publication Date:
January 18, 2001
Filing Date:
July 09, 1999
Export Citation:
Assignee:
UBE INDUSTRIES (JP)
HARADA KATSUMASA (JP)
NISHINO SHIGEYOSHI (JP)
YOSHII KIYOTAKA (JP)
HARADA KATSUMASA (JP)
NISHINO SHIGEYOSHI (JP)
YOSHII KIYOTAKA (JP)
International Classes:
A61K31/55; A61K31/554; A61P25/18; C07C319/14; C07D281/16; C07C323/62; (IPC1-7): C07D281/16; C07C323/62
Domestic Patent References:
| WO1992019607A1 | 1992-11-12 |
Foreign References:
| JPH11199574A | 1999-07-27 |
Other References:
FRANCIS BENNETT,, J. HETEROCYCL. CHEM, vol. 12, no. 6, December 1975 (1975-12-01), XP002926383
O. FRANCIS BENNETT ET AL., J. HETEROCYCL. CHEM., vol. 12, no. 6, December 1975 (1975-12-01), pages 1211 - 1213
M. KUTI; J. RABAI; I. KAPOVITS, PHOSPHORUS, SULFUR, AND SILICON, vol. 85, 1993, pages 119 - 127
See also references of EP 1201663A4
O. FRANCIS BENNETT ET AL., J. HETEROCYCL. CHEM., vol. 12, no. 6, December 1975 (1975-12-01), pages 1211 - 1213
M. KUTI; J. RABAI; I. KAPOVITS, PHOSPHORUS, SULFUR, AND SILICON, vol. 85, 1993, pages 119 - 127
See also references of EP 1201663A4
Attorney, Agent or Firm:
Yanagawa, Yasuo (Yotsuya Shinjuku-ku Tokyo, JP)
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