Title:
PROCESSES FOR PRODUCING 2-CHLORO-3-TRIFLUOROMETHYLPYRIDINE
Document Type and Number:
WIPO Patent Application WO/2011/078296
Kind Code:
A1
Abstract:
Processes are provided by which 2-chloro-3-trifluoromethylpyridine, which is useful as an intermediate for medicines and agrochemicals, is produced at a high production rate in high yield. One process for producing 2-chloro-3-trifluoromethylpyridine or a salt thereof is characterized by reacting 3-trifluoromethylpyridine N-oxide with a chlorinating agent. Another is characterized by oxidizing 3-trifluoromethylpyridine to produce 3-trifluoromethylpyridine N-oxide and subsequently reacting the obtained 3-trifluoromethylpyridine N-oxide with a chlorinating agent.
Inventors:
FUKUI FUMIHIRO
Application Number:
PCT/JP2010/073252
Publication Date:
June 30, 2011
Filing Date:
December 22, 2010
Export Citation:
Assignee:
ISHIHARA SANGYO KAISHA (JP)
FUKUI FUMIHIRO
FUKUI FUMIHIRO
International Classes:
C07D213/61
Foreign References:
| JPS5581860A | 1980-06-20 | |||
| JPS55122762A | 1980-09-20 | |||
| JP2009531439A | 2009-09-03 | |||
| US4393214A | 1983-07-12 | |||
| JPS55122762A | 1980-09-20 | |||
| JP2009293768A | 2009-12-17 |
Other References:
YAMANAKA, H. ET AL.: "Site-Selectivity in the Reaction of 3-Substituted Pyridine 1-Oxides with Phosphoryl Chloride", CHEM. PHARM. BULL., vol. 36, no. 6, 1988, pages 2244 - 2247
CHEM. PHARM. BULL., vol. 36, no. 6, 1988, pages 2244 - 2247
See also references of EP 2520569A4
CHEM. PHARM. BULL., vol. 36, no. 6, 1988, pages 2244 - 2247
See also references of EP 2520569A4
Attorney, Agent or Firm:
OGURI Shohei et al. (JP)
Shohei Oguri (JP)
Shohei Oguri (JP)
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