Title:
PROCESSES FOR PRODUCING CYANOPHENYL DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1999/061411
Kind Code:
A1
Abstract:
A process for producing a cyanobenzaldehyde compound which comprises using an oxidizing agent to convert the aminomethyl group of a cyanobenzylamine compound to an aldehyde group without impairing the cyano group; a process for producing a cyanobenzoyl halide compound which comprises converting the aldehyde group of a cyanobenzaldehyde compound to an acid halide group without impairing the cyano group; and a process for producing a cyanobenzoic acid compound which comprises reacting a cyanobenzaldehyde compound with a hypohalogenous acid. The cyanophenyl derivatives, useful as intermediates for medicines, agricultural chemicals, liquid crystals, functional high-molecular monomers, etc., can be efficiently produced from easily available materials.
Inventors:
YASUDA HIROSHI (JP)
OHSHIRO KIMITAKA (JP)
NOZAWA KANEO (JP)
MORIKAWA KOHEI (JP)
OHSHIRO KIMITAKA (JP)
NOZAWA KANEO (JP)
MORIKAWA KOHEI (JP)
Application Number:
PCT/JP1999/002857
Publication Date:
December 02, 1999
Filing Date:
May 28, 1999
Export Citation:
Assignee:
SHOWA DENKO KK (JP)
YASUDA HIROSHI (JP)
OHSHIRO KIMITAKA (JP)
NOZAWA KANEO (JP)
MORIKAWA KOHEI (JP)
YASUDA HIROSHI (JP)
OHSHIRO KIMITAKA (JP)
NOZAWA KANEO (JP)
MORIKAWA KOHEI (JP)
International Classes:
C07C253/30; C07C255/56; C07C255/57; (IPC1-7): C07C253/30; C07C255/56; C07C255/57
Foreign References:
| JPH0967302A | 1997-03-11 |
Other References:
SMITH J R L, MORTIMER D N: "OXIDATIVE N-DEALKYLATION OF N,N-DIMETHYLBENZYLAMINES BY METALLOPORPHYRIN-CATALYSED MODEL SYSTEMS FOR CYTOCHROME P450 MONO-OXYGENASES", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS., CHEMICAL SOCIETY. LETCHWORTH., GB, 1 January 1985 (1985-01-01), GB, pages 64/65, XP002919776, ISSN: 0022-4936, DOI: 10.1039/c39850000064
SEMMELHACK M F, SCHMID C R: "NITROXYL-MEDIATED ELECTROOXIDATION OF AMINES TO NITRILES AND CARBONYL COMPOUNDS", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, US, vol. 105, no. 22, 1 January 1983 (1983-01-01), US, pages 6732 - 6734, XP002919777, ISSN: 0002-7863, DOI: 10.1021/ja00360a042
SASSON Y, ZAPPI G D, NEUMANN R: "LIQUID-PHASE OXIDATION OF DEACTIVATED METHYLBENZENES BY AQUEOUS SODIUM HYPOCHLORITE CATALYZED BY RUTHENIUM SALTS UNDER PHASE-TRANSFER CATALYTIC CONDITIONS", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 51, 1 January 1986 (1986-01-01), US, pages 2880 - 2883, XP002919778, ISSN: 0022-3263, DOI: 10.1021/jo00365a005
PUNNIYAMURTHY T, SWINDER JEET SINGH KALRA, JAVED IQBAL: "COBALT CATALYSED SYNTHESIS OF 1,2-DIONES FROM AROMATIC ALDEHYDES INTHE PRESENCE OF N-BUTANAL", TETRAHEDRON LETTERS, PERGAMON, GB, vol. 35, no. 18, 1 January 1994 (1994-01-01), GB, pages 2959/2960, XP002919779, ISSN: 0040-4039, DOI: 10.1016/S0040-4039(00)76671-8
MCKILLOP A, KEMP D: "FURTHER FUNCTIONAL GROUP OXIDATIONS USING SODIUM PERBORATE", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 45, no. 11, 1 January 1989 (1989-01-01), AMSTERDAM, NL, pages 3299 - 3306, XP002919780, ISSN: 0040-4020, DOI: 10.1016/S0040-4020(01)81008-5
See also references of EP 1083165A4
SEMMELHACK M F, SCHMID C R: "NITROXYL-MEDIATED ELECTROOXIDATION OF AMINES TO NITRILES AND CARBONYL COMPOUNDS", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, US, vol. 105, no. 22, 1 January 1983 (1983-01-01), US, pages 6732 - 6734, XP002919777, ISSN: 0002-7863, DOI: 10.1021/ja00360a042
SASSON Y, ZAPPI G D, NEUMANN R: "LIQUID-PHASE OXIDATION OF DEACTIVATED METHYLBENZENES BY AQUEOUS SODIUM HYPOCHLORITE CATALYZED BY RUTHENIUM SALTS UNDER PHASE-TRANSFER CATALYTIC CONDITIONS", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 51, 1 January 1986 (1986-01-01), US, pages 2880 - 2883, XP002919778, ISSN: 0022-3263, DOI: 10.1021/jo00365a005
PUNNIYAMURTHY T, SWINDER JEET SINGH KALRA, JAVED IQBAL: "COBALT CATALYSED SYNTHESIS OF 1,2-DIONES FROM AROMATIC ALDEHYDES INTHE PRESENCE OF N-BUTANAL", TETRAHEDRON LETTERS, PERGAMON, GB, vol. 35, no. 18, 1 January 1994 (1994-01-01), GB, pages 2959/2960, XP002919779, ISSN: 0040-4039, DOI: 10.1016/S0040-4039(00)76671-8
MCKILLOP A, KEMP D: "FURTHER FUNCTIONAL GROUP OXIDATIONS USING SODIUM PERBORATE", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 45, no. 11, 1 January 1989 (1989-01-01), AMSTERDAM, NL, pages 3299 - 3306, XP002919780, ISSN: 0040-4020, DOI: 10.1016/S0040-4020(01)81008-5
See also references of EP 1083165A4
Attorney, Agent or Firm:
Ohie, Kunihisa (Nihonbashi-Ningyocho 2-chome Chuo-ku Tokyo, JP)
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