Title:
PRODUCTION METHOD FOR CRYSTAL OF REDUCED COENZYME Q10 HAVING EXCELLENT STABILITY
Document Type and Number:
WIPO Patent Application WO/2020/045571
Kind Code:
A1
Abstract:
Provided is a production method for efficiently producing form II crystal of reduced coenzyme Q10. This production method for form II crystal of reduced coenzyme Q10 according to the present invention includes: formulating a liquid mixture by adding form II crystal of reduced coenzyme Q10 as seed crystal to a solution having a temperature of 32-43°C and containing reduced coenzyme Q10 and at least one organic solvent selected from the group consisting of alcohols, hydrocarbons, fatty acid esters, and nitrogen compounds; and precipitating the crystal in the liquid mixture.
Inventors:
YAMAGUCHI TAKAO (JP)
KINOSHITA KOICHI (JP)
KINOSHITA KOICHI (JP)
Application Number:
PCT/JP2019/033923
Publication Date:
March 05, 2020
Filing Date:
August 29, 2019
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
C07C41/40; C07C43/23
Domestic Patent References:
| WO2012176842A1 | 2012-12-27 | |||
| WO2003006409A1 | 2003-01-23 | |||
| WO2003006409A1 | 2003-01-23 | |||
| WO2012176842A1 | 2012-12-27 |
Foreign References:
| JP2007332162A | 2007-12-27 | |||
| JP2015131766A | 2015-07-23 | |||
| JPH10109933A | 1998-04-28 | |||
| JP2003089669A | 2003-03-28 | |||
| JP2018161790A | 2018-10-18 |
Other References:
See also references of EP 3845515A4
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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