THE PRODUCTION OF MOLECULAR ARRAYS - IMP COLLEGE INNOVATIONS LTD

Title:

THE PRODUCTION OF MOLECULAR ARRAYS

Document Type and Number:

WIPO Patent Application WO2002102504

Kind Code:

A3

Abstract:

A method for the production of an array of molecules immobilised on a substrate, comprises the deposition of the molecules from a micropipette containing them, onto the substrate, in a liquid environment, wherein the distance of the micropipette from the substrate is controlled in response to the ion current in the liquid. This method is particularly suitable for the deposition of biological molecules.

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Inventors:

KORCHEV YURI EVGENIEVICH (GB)
KLENERMAN DAVID (GB)
ABELL CHRISTOPHER (GB)
YING LIMING (GB)
BRUCKBAUER ANDREAS (GB)

Application Number:

PCT/GB2002/002727

Publication Date:

March 06, 2003

Filing Date:

June 13, 2002

Export Citation:

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Assignee:

IMP COLLEGE INNOVATIONS LTD (GB)
KORCHEV YURI EVGENIEVICH (GB)
KLENERMAN DAVID (GB)
ABELL CHRISTOPHER (GB)
YING LIMING (GB)
BRUCKBAUER ANDREAS (GB)

International Classes:

B82B3/00; G01N27/416; G01N37/00; G01Q80/00; (IPC1-7): G01N27/416

Foreign References:

US5730940A	1998-03-24
DE19542620A1	1997-05-22
US4924091A	1990-05-08

Other References:

HAIJUN ZHANG: "electrochemical microprocess by scanning ion-conductance microscopy", J. VAC. SCI. TECHNOL. B, vol. 17, no. 2, 1999, US, pages 269 - 272, XP001059438
G. MACBEATH: "Printing proteins as microarrays for high throughput function determination", SCIENCE, vol. 289, 8 September 2000 (2000-09-08), pages 1760 - 1763, XP002190973
R. D. PINER: "Dip-pen Nanolithography", SCIENCE, vol. 283, 1999, pages 661 - 663, XP000971021
A. D. MÜLLER: "Electrochemical pattern formation in a scanning near-field optical microscope", APPLIED PHYSICS A, MATERIALS SCIENCE & PROCESSING, vol. A66, no. 1sup, 1998, pages s453 - s456, XP001059735

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