Title:
PROPHYLACTIC OR THERAPEUTIC AGENT FOR DISEASE INDUCED BY OXIDATIVE STRESS
Document Type and Number:
WIPO Patent Application WO/2019/235577
Kind Code:
A1
Abstract:
[Problem] The problem is to provide a medicine or the like which can prevent or treat a disease induced by oxidative stress.
[Solution] A prophylactic or therapeutic agent for a disease induced by oxidative stress, a pharmaceutical composition, a medical device, a hygiene article, a food, or a beverage is provided, which contains silicon microparticles. A disease induced by oxidative stress can be prevented or treated by orally administering silicon microparticles or placing silicon microparticles on the skin or a mucosa. Examples of the disease induced by oxidative stress include an inflammatory disease and depression. The silicon microparticles have an excellent prophylactic/therapeutic effect.
Inventors:
SHIMADA SHOICHI (JP)
KOYAMA YOSHIHISA (JP)
KONDO MAKOTO (JP)
USUI NORIYOSHI (JP)
OHATA KAZUYA (JP)
INOHARA HIDENORI (JP)
KOBAYASHI HIKARU (JP)
KOBAYASHI YUKI (JP)
KOYAMA YOSHIHISA (JP)
KONDO MAKOTO (JP)
USUI NORIYOSHI (JP)
OHATA KAZUYA (JP)
INOHARA HIDENORI (JP)
KOBAYASHI HIKARU (JP)
KOBAYASHI YUKI (JP)
Application Number:
PCT/JP2019/022558
Publication Date:
December 12, 2019
Filing Date:
June 06, 2019
Export Citation:
Assignee:
UNIV OSAKA (JP)
International Classes:
A61K33/00; A61P1/04; A61P29/00; A61P39/06
Domestic Patent References:
| WO2017130709A1 | 2017-08-03 | |||
| WO2018037818A1 | 2018-03-01 | |||
| WO2017130709A1 | 2017-08-03 | |||
| WO2018037752A1 | 2018-03-01 | |||
| WO2018037818A1 | 2018-03-01 | |||
| WO2018037819A1 | 2018-03-01 |
Foreign References:
| JPH10168095A | 1998-06-23 | |||
| JP2016155118A | 2016-09-01 | |||
| JP2017104848A | 2017-06-15 |
Other References:
JUN SATO , MAYURI SAKANO , HAJIME ASANO , MAMI OKADA , HIROYUKI SUZUKI : "Effect of Mesalazine in Rat Models of Inflammatory Bowel Disease", JAPANESE PHARMACOLOGY & THERAPEUTICS, vol. 36, no. 4, 2008, pages 293 - 301, XP009524917, ISSN: 0386-3603
YAN H ET AL., INT J CLIN EXP MED, vol. 8, no. 11, 15 November 2015 (2015-11-15), pages 20245 - 53
SHINSUKE MATSUDA ET AL.: "Extended Abstracts of The 62nd JSAP", 2015, SPRING, article "Concentration of hydrogen molecules and splitting water using silicon nanoparticle"
MANDEL RJRANDALL PK, BRAIN RES BULL, vol. 24, no. 2, February 1990 (1990-02-01), pages 175 - 80
COSTALL BKELLY MENAYLOR RJ, NEUROPHARMACOLOGY, vol. 22, no. 3, March 1983 (1983-03-01), pages 295 - 302
CHOW KH ET AL., J VIS EXP, no. 109, 25 March 2016 (2016-03-25), pages e53643
BEDERSON, STROKE, vol. 17, no. 3, 1986
THE JOURNAL OF NEUROSCIENCE, vol. 15, no. 7, July 1995 (1995-07-01), pages 5372 - 5378
See also references of EP 3804732A4
YAN H ET AL., INT J CLIN EXP MED, vol. 8, no. 11, 15 November 2015 (2015-11-15), pages 20245 - 53
SHINSUKE MATSUDA ET AL.: "Extended Abstracts of The 62nd JSAP", 2015, SPRING, article "Concentration of hydrogen molecules and splitting water using silicon nanoparticle"
MANDEL RJRANDALL PK, BRAIN RES BULL, vol. 24, no. 2, February 1990 (1990-02-01), pages 175 - 80
COSTALL BKELLY MENAYLOR RJ, NEUROPHARMACOLOGY, vol. 22, no. 3, March 1983 (1983-03-01), pages 295 - 302
CHOW KH ET AL., J VIS EXP, no. 109, 25 March 2016 (2016-03-25), pages e53643
BEDERSON, STROKE, vol. 17, no. 3, 1986
THE JOURNAL OF NEUROSCIENCE, vol. 15, no. 7, July 1995 (1995-07-01), pages 5372 - 5378
See also references of EP 3804732A4
Attorney, Agent or Firm:
SHOJI Takashi et al. (JP)
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