Title:
PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR DYSMENORRHEA
Document Type and Number:
WIPO Patent Application WO/2010/147184
Kind Code:
A1
Abstract:
Disclosed is a prophylactic and/or therapeutic agent for dysmenorrhea and/or dysmenorrhea-related conditions.
Specifically disclosed is a prophylactic and/or therapeutic agent for dysmenorrhea and/or dysmenorrhea-related conditions, which comprises tranilast as an active ingredient.
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Inventors:
KATABUCHI HIDETAKA (JP)
HONDA RITSUO (JP)
SAYA HIDEYUKI (JP)
ARIMA YOSHIMI (JP)
NIWA SHINICHIRO (JP)
MAKINO YASUTAKA (JP)
HONDA RITSUO (JP)
SAYA HIDEYUKI (JP)
ARIMA YOSHIMI (JP)
NIWA SHINICHIRO (JP)
MAKINO YASUTAKA (JP)
Application Number:
PCT/JP2010/060301
Publication Date:
December 23, 2010
Filing Date:
June 17, 2010
Export Citation:
Assignee:
UNIV KUMAMOTO NAT UNIV CORP (JP)
UNIV KEIO (JP)
LINK GENOMICS INC (JP)
KATABUCHI HIDETAKA (JP)
HONDA RITSUO (JP)
SAYA HIDEYUKI (JP)
ARIMA YOSHIMI (JP)
NIWA SHINICHIRO (JP)
MAKINO YASUTAKA (JP)
UNIV KEIO (JP)
LINK GENOMICS INC (JP)
KATABUCHI HIDETAKA (JP)
HONDA RITSUO (JP)
SAYA HIDEYUKI (JP)
ARIMA YOSHIMI (JP)
NIWA SHINICHIRO (JP)
MAKINO YASUTAKA (JP)
International Classes:
A61K31/196; A61P1/10; A61P1/12; A61P7/06; A61P15/00; A61P25/04; A61P25/18; A61P29/00
Domestic Patent References:
| WO1997029744A1 | 1997-08-21 | |||
| WO2001005394A1 | 2001-01-25 | |||
| WO2001013911A1 | 2001-03-01 | |||
| WO2001013952A1 | 2001-03-01 | |||
| WO2001025190A1 | 2001-04-12 |
Foreign References:
| JP2002187855A | 2002-07-05 | |||
| JP2003508544A | 2003-03-04 | |||
| JPH05163222A | 1993-06-29 | |||
| JPH06135829A | 1994-05-17 | |||
| JPH07277966A | 1995-10-24 | |||
| JPH09227371A | 1997-09-02 | |||
| JPS4993335A | 1974-09-05 | |||
| US3940422A | 1976-02-24 |
Other References:
SHIME, H. ET AL.: "Tranilast inhibits the proliferation of uterine leiomyoma cells in vitro through Gl arrest associated with the induction of p21waf1 and p53", JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, vol. 87, no. 12, 2002, pages 5610 - 7, XP008150267
TOMOKI KANEYAMA ET AL.: "UUO Rat ni Okeru Tranilast no Nyosaikan Johisaibo EMT Yokusei Koka no Kaiseki", THE JAPANESE JOURNAL OF NEPHROLOGY, vol. 51, no. 3, 25 April 2009 (2009-04-25), pages 267, XP008150284
SAEGUSA, M. ET AL.: "Requirement of the Akt/p- Catenin Pathway for Uterine Carcinosarcoma Genesis, Modulating E-Cadherin Expression Through the Transactivation of Slug", THE AMERICAN JOURNAL OF PATHOLOGY, vol. 174, no. 6, 23 April 2009 (2009-04-23), pages 2107 - 15, XP008150281
GRUND, E. M. ET AL.: "Tumor Necrosis Factor-a Regulates Inflammatory and Mesenchymal Responses via Mitogen-Activated Protein Kinase Kinase, p38, and Nuclear Factor KB in Human Endometriotic Epithelial Cells", MOLECULAR PHARMACOLOGY, vol. 73, no. 5, 2008, pages 1394 - 404, XP008150282
RITSUO HONDA ET AL.: "Fujin no Yotsu no Gen'in Shikkan no Shindan to Chiryo", RINSHO TO KENKYU, vol. 80, no. 3, 2003, pages 35417 - 38420, XP008150285
See also references of EP 2455077A4
MODERN PHYSICIAN, vol. 29, no. 3, 2009, pages 399
"10th Revision Version for 2007", 2007, article "International Statistical Classification of Diseases and Related Health Problems"
"Voltaren Tablets, Interview Form(Revised 9th Edition),", June 2005, pages: 11 I
UNKNOWN: "Ibuprofen Tablets/Ibuprofen Powder, Interview Form(13th Edition)", January 2010
UNKNOWN: "Naproxen Tablets/Naproxen Capsules, Interview Form(11 th Edition)", October 2009
LUNABELL: "Interview Form(New Form 4th Edition),", January 2010, pages: 30,31,9
NUTTALL I.D. ET AL., CONTRACEPTION, vol. 25, 1982, pages 463 - 469
JOURNAL OF MAMMALIAN OVA RESEARCH, vol. 23, 2006, pages 163
"Pharmaceutical Interview Form, 2nd edition,", July 2006, KISSEI PHARMACEUTICAL CO., LTD., pages: 19
TOMOKI KANEYAMA ET AL.: "UUO Rat ni Okeru Tranilast no Nyosaikan Johisaibo EMT Yokusei Koka no Kaiseki", THE JAPANESE JOURNAL OF NEPHROLOGY, vol. 51, no. 3, 25 April 2009 (2009-04-25), pages 267, XP008150284
SAEGUSA, M. ET AL.: "Requirement of the Akt/p- Catenin Pathway for Uterine Carcinosarcoma Genesis, Modulating E-Cadherin Expression Through the Transactivation of Slug", THE AMERICAN JOURNAL OF PATHOLOGY, vol. 174, no. 6, 23 April 2009 (2009-04-23), pages 2107 - 15, XP008150281
GRUND, E. M. ET AL.: "Tumor Necrosis Factor-a Regulates Inflammatory and Mesenchymal Responses via Mitogen-Activated Protein Kinase Kinase, p38, and Nuclear Factor KB in Human Endometriotic Epithelial Cells", MOLECULAR PHARMACOLOGY, vol. 73, no. 5, 2008, pages 1394 - 404, XP008150282
RITSUO HONDA ET AL.: "Fujin no Yotsu no Gen'in Shikkan no Shindan to Chiryo", RINSHO TO KENKYU, vol. 80, no. 3, 2003, pages 35417 - 38420, XP008150285
See also references of EP 2455077A4
MODERN PHYSICIAN, vol. 29, no. 3, 2009, pages 399
"10th Revision Version for 2007", 2007, article "International Statistical Classification of Diseases and Related Health Problems"
"Voltaren Tablets, Interview Form(Revised 9th Edition),", June 2005, pages: 11 I
UNKNOWN: "Ibuprofen Tablets/Ibuprofen Powder, Interview Form(13th Edition)", January 2010
UNKNOWN: "Naproxen Tablets/Naproxen Capsules, Interview Form(11 th Edition)", October 2009
LUNABELL: "Interview Form(New Form 4th Edition),", January 2010, pages: 30,31,9
NUTTALL I.D. ET AL., CONTRACEPTION, vol. 25, 1982, pages 463 - 469
JOURNAL OF MAMMALIAN OVA RESEARCH, vol. 23, 2006, pages 163
"Pharmaceutical Interview Form, 2nd edition,", July 2006, KISSEI PHARMACEUTICAL CO., LTD., pages: 19
Attorney, Agent or Firm:
KOBAYASHI Hiroshi et al. (JP)
Kobayashi 浩 (JP)
Kobayashi 浩 (JP)
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