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Title:
PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Document Type and Number:
WIPO Patent Application WO/2010/035751
Kind Code:
A1
Abstract:
Provided is a prophylactic and/or therapeutic agent which improves abnormalities of intestinal function in the form of abdominal pain, diarrhoea or constipation, and is useful for preventing or treating functional gastrointestinal disorders. The prophylactic and/or therapeutic agent for functional gastrointestinal disorders contains rifaximin as an active ingredient. Functional gastrointestinal disorders include conditions such as functional oesophageal disorders, functional gastroduodenal disorders (for example, functional dyspepsia), functional intestinal disorders (for example, functional abdominal distension and functional diarrhoea), functional abdominal pain syndrome, gall bladder dysfunction and sphincter of Oddi dysfunction, functional anorectal disorders (for example, functional incontinence, functional anorectal pain and functional defecation disorders), neonatal and paediatric functional disorders (for example, paediatric functional diarrhoea), and functional disorders of infancy and adolescence (for example, paediatric functional abdominal pain and paediatric nonconservative incontinence).

Inventors:
TAMAOKI SATORU (JP)
SATO JUN (JP)
SUDO KATSUICHI (JP)
Application Number:
PCT/JP2009/066533
Publication Date:
April 01, 2010
Filing Date:
September 24, 2009
Export Citation:
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Assignee:
ASKA PHARM CO LTD (JP)
TAMAOKI SATORU (JP)
SATO JUN (JP)
SUDO KATSUICHI (JP)
International Classes:
A61K31/439; A61P1/00; A61P1/06; A61P1/10; A61P1/12
Domestic Patent References:
WO2008016708A22008-02-07
WO2007103448A22007-09-13
WO2001011077A22001-02-15
WO2006094662A12006-09-14
Foreign References:
JPS6123192A1986-01-31
JPS6123192B21986-06-04
JP2834951B21998-12-14
JP2755550B21998-05-20
JPH10226645A1998-08-25
JP2007509904A2007-04-19
Other References:
PIMENTEL M ET AL., ANNALS OF INTERNAL MEDICINE, vol. 145, no. 8, 2006, pages 557 - 563, XP008140626
FUMI A L ET AL., THE ANNALS OF PHARMACOTHERAPY, vol. 42, March 2008 (2008-03-01), pages 408 - 412, XP008143976
LEMBO A J ET AL., PRACTICAL GASTROENTEROLOGY, September 2007 (2007-09-01), pages 33 - 36, XP008143975
GASTROENTEROL, vol. 130, 2006, pages 1377 - 1390
ANNALS OF INTERNAL MEDICINE, vol. 142, no. 10, 2005, pages 805 - 812
ANNALS OF INTERNAL MEDICINE, vol. 145, no. 8, 2006, pages 557 - 563
ALIMENT PHARMACOL THER., vol. 24, no. 2, 14 July 2006 (2006-07-14), pages 405
"Handbook of Pharmaceutical Excipients", 1989, MARUZEN COMPANY, LTD.
"Japanese Pharmaceutical Excipients Dictionary", March 2002, YAKUJI NIPPO LTD.
"Japanese Pharmaceutical Excipients Dictionary", May 2005, YAKUJI NIPPO LTD.
"Pharmaceutics, revised fifth", 1997, NANKODO, CO., LTD.
"Pharmaceutical Excipients", August 2003, YAKUJI NIPPO LTD.
See also references of EP 2327407A4
Attorney, Agent or Firm:
KUWATA MITSUO (JP)
Atsuo Kuwata (JP)
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