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Title:
PROPOFOL-CONTAINING OIL-IN-WATER EMULSION COMPOSITION AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO/2016/047664
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a propofol-containing oil-in-water emulsion composition that is highly stable even when filled into a plastic container, and a method for producing the same. The present invention provides a propofol-containing oil-in-water emulsion composition comprising: at least one selected from the group consisting of tris-hydroxymethylaminomethane, phosphoric acid, and triethanolamine; propofol; an oil component; an emulsifier; and water. The dissolved oxygen concentration is 5 mg/L or less and the average particle diameter of the emulsion is 180 nm or less.

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Inventors:
SAKATA YOSHINORI (JP)
IZUMI YASUYUKI (JP)
TSUJIHATA SHIGETOMO (JP)
Application Number:
PCT/JP2015/076870
Publication Date:
March 31, 2016
Filing Date:
September 24, 2015
Export Citation:
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Assignee:
FUJIFILM CORP (JP)
International Classes:
A61K31/05; A61K9/107; A61K47/12; A61K47/18; A61K47/20; A61K47/24; A61P23/00
Domestic Patent References:
WO2006112276A12006-10-26
Foreign References:
CN102805728A2012-12-05
JP2004526730A2004-09-02
JP2012210315A2012-11-01
JP2006504771A2006-02-09
US6177477B12001-01-23
JP2010534555A2010-11-11
Other References:
See also references of EP 3199150A4
Attorney, Agent or Firm:
SIKs & Co. (JP)
Patent business corporation patent firm Sykes (JP)
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