Title:
PROTEIN PRODUCTION SYSTEM
Document Type and Number:
WIPO Patent Application WO2001029204
Kind Code:
A3
Abstract:
The invention relates to a method for producing a protein of interest, comprising transforming an insect with a non-viral expression system capable of expressing the protein of interest in the larvae of the insect; breeding the insect to produce larvae; culturing the larvae; and isolating the protein of interest from the larvae. The transformation is advantageously performed by means of a transposon vector.
More Like This:
| JP2001286849 | GARBAGE TREATING DEVICE |
| WO/2001/072132 | NON-HUMAN TRANSGENIC ANIMALS EXPRESSING PLATELET-DERIVED GROWTH FACTOR C (PDGF-C) AND USES THEREOF |
| WO/2000/032540 | WORM FARM |
Inventors:
CRAIG ROGER (GB)
SAVAKIS CHARALAMBOS (GR)
SAVAKIS CHARALAMBOS (GR)
Application Number:
PCT/GB2000/004013
Publication Date:
November 01, 2001
Filing Date:
October 19, 2000
Export Citation:
Assignee:
CRAIG ROGER (GB)
SAVAKIS CHARALAMBOS (GR)
SAVAKIS CHARALAMBOS (GR)
International Classes:
A01K67/033; C07K14/435; C07K14/47; C07K14/61; C12N9/22; C12N9/24; C12N15/09; C12N15/90; C12P21/02; (IPC1-7): C12N15/90; C12N15/54; C12N9/22; A01K67/033; C12P21/02; C07K14/61; C07K14/47; C12N9/24
Domestic Patent References:
| WO1990001556A1 | 1990-02-22 | |||
| WO1993006224A1 | 1993-04-01 |
Foreign References:
| US5840865A | 1998-11-24 |
Other References:
DATABASE WPI Week 199718, Derwent World Patents Index; AN 1997-193471, XP002164516, QIN J ET AL: "Recombination of human macrophage colony stimulating factor by domestic silkworm gene engineering"
PHAM M ET AL: "Human interleukin-2 production in insect (Trichoplusia ni) larvae: effects and partial control of proteolysis", BIOTECHNOL. BIOENG., vol. 62, no. 2, 20 January 1999 (1999-01-20), pages 175 - 182, XP002164514
LOUKERIS T G ET AL: "GENE TRANSFER INTO THE MEDFLY, CERATITIS CAPITATA, WITH A DROSOPHILA HYDEI TRANSPOSABLE ELEMENT", SCIENCE,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,,US, vol. 270, no. 5244, 22 December 1995 (1995-12-22), pages 2002 - 2005, XP000941764, ISSN: 0036-8075
LOUKERIS T ET AL: "Introduction of the transposable element Minos into the germ line of Drosophila melanogaster", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., vol. 92, no. 21, 10 October 1995 (1995-10-10), pages 9485 - 9489, XP002164515
PLASTERK R H A ET AL: "Resident aliens: the Tc1/mariner superfamily of transposable elements", TRENDS IN GENETICS,NL,ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, vol. 15, no. 8, 1 August 1999 (1999-08-01), pages 326 - 332, XP004172552, ISSN: 0168-9525
JOWETT T ET AL: "MAMMALIAN GENES EXPRESSED IN DROSOPHILA: A TRANSGENIC MODEL FOR THESTUDY OF MECHANISMS OF CHEMICAL MUTAGENESIS AND METABOLISM", EMBO JOURNAL,GB,OXFORD UNIVERSITY PRESS, SURREY, vol. 10, no. 5, 1991, pages 1075 - 1081, XP000770307, ISSN: 0261-4189
RANCOURT D E ET AL: "DIFFERENTIAL TRANSLATABILITY OF ANTIFREEZE PROTEIN MRNAS IN A TRANSGENIC HOST", BIOCHIMICA ET BIOPHYSICA ACTA. GENE STRUCTURE AND EXPRESSION,NL,ELSEVIER, AMSTERDAM, vol. 1129, no. 2, 1992, pages 188 - 194, XP000199687, ISSN: 0167-4781
PHAM M ET AL: "Human interleukin-2 production in insect (Trichoplusia ni) larvae: effects and partial control of proteolysis", BIOTECHNOL. BIOENG., vol. 62, no. 2, 20 January 1999 (1999-01-20), pages 175 - 182, XP002164514
LOUKERIS T G ET AL: "GENE TRANSFER INTO THE MEDFLY, CERATITIS CAPITATA, WITH A DROSOPHILA HYDEI TRANSPOSABLE ELEMENT", SCIENCE,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,,US, vol. 270, no. 5244, 22 December 1995 (1995-12-22), pages 2002 - 2005, XP000941764, ISSN: 0036-8075
LOUKERIS T ET AL: "Introduction of the transposable element Minos into the germ line of Drosophila melanogaster", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., vol. 92, no. 21, 10 October 1995 (1995-10-10), pages 9485 - 9489, XP002164515
PLASTERK R H A ET AL: "Resident aliens: the Tc1/mariner superfamily of transposable elements", TRENDS IN GENETICS,NL,ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, vol. 15, no. 8, 1 August 1999 (1999-08-01), pages 326 - 332, XP004172552, ISSN: 0168-9525
JOWETT T ET AL: "MAMMALIAN GENES EXPRESSED IN DROSOPHILA: A TRANSGENIC MODEL FOR THESTUDY OF MECHANISMS OF CHEMICAL MUTAGENESIS AND METABOLISM", EMBO JOURNAL,GB,OXFORD UNIVERSITY PRESS, SURREY, vol. 10, no. 5, 1991, pages 1075 - 1081, XP000770307, ISSN: 0261-4189
RANCOURT D E ET AL: "DIFFERENTIAL TRANSLATABILITY OF ANTIFREEZE PROTEIN MRNAS IN A TRANSGENIC HOST", BIOCHIMICA ET BIOPHYSICA ACTA. GENE STRUCTURE AND EXPRESSION,NL,ELSEVIER, AMSTERDAM, vol. 1129, no. 2, 1992, pages 188 - 194, XP000199687, ISSN: 0167-4781
Download PDF: