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Title:
PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION
Document Type and Number:
WIPO Patent Application WO/2010/126045
Kind Code:
A1
Abstract:
A compound represented by general formula [1] or a salt thereof, which is a novel cyanine dye derivative having a high fluorescence intensity in a short-wavelength region. The cyanine dye derivative has a structure comprising a pyrazole skeleton and an indole skeleton combined therewith through a polymethine chain, and has been rendered controllable with respect to electrophoretic mobility by further introducing a quaternary ammonium cation into a molecule having that structure. (In formula [1], R1 to R6 each independently represents, for example, an alkyl having a substituent represented by general formula [101], R7 to R10 each independently represents a hydrogen atom, etc., R11 represents a hydrogen atom, an alkyl, etc., and n is an integer of 0-3, at least one of R1 to R6 being an alkyl having a substituent represented by general formula [101].)

Inventors:
YAMAMOTO NAOYUKI (JP)
KUROSAWA TATSUO (JP)
HASABA SATOSHI (JP)
DATE MUTSUHIRO (JP)
Application Number:
PCT/JP2010/057467
Publication Date:
November 04, 2010
Filing Date:
April 27, 2010
Export Citation:
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Assignee:
WAKO PURE CHEM IND LTD (JP)
YAMAMOTO NAOYUKI (JP)
KUROSAWA TATSUO (JP)
HASABA SATOSHI (JP)
DATE MUTSUHIRO (JP)
International Classes:
C07D403/06; C09B23/00; G01N21/78
Domestic Patent References:
WO2007114398A12007-10-11
WO1999005221A11999-02-04
WO1998015829A11998-04-16
WO2001002374A12001-01-11
WO2007114398A12007-10-11
Foreign References:
US5268486A1993-12-07
US5486616A1996-01-23
US5569766A1996-10-29
JP2003034696A2003-02-07
JP2003034697A2003-02-07
US5571388A1996-11-05
US5800995A1998-09-01
Other References:
See also references of EP 2426123A4
JOURNAL OF ORGANIC CHEMISTRY, vol. 42, no. 14, 1977, pages 2474 - 80
J. CHEM. SOC. , PERKIN TRANS., vol. 1, 1984, pages 947 - 952
"Modern Synthetic Reactions", 1972, pages: 492,510,
ADV. HETEROCYCLE. CHEM., vol. 34, 1983, pages 53 - 78
TAKEHIKO KITAMORI ET AL.: "Technology and applications of micro chemical chip", 2004, MARUZEN CO., LTD.
POSER JW; PRICE PA, J. BIOL. CHEM., vol. 254, no. 2, 25 January 1979 (1979-01-25), pages 431 - 6
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