Title:
PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/063050
Kind Code:
A1
Abstract:
The present invention relates to a pyrazole compound and a preparation method therefor and a use thereof. In particular, the present invention relates to a compound shown in formula I, a pharmaceutical composition containing same or a pharmaceutically acceptable form thereof, a pharmaceutical composition thereof, a preparation method therefor, and a use thereof. The compound can be used as a drug for treating cancer or fibrosis disease, (I).
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Inventors:
TIAN QIANG (CN)
ZHANG YITAO (CN)
JIANG XIAOLING (CN)
LIU CHUNCHI (CN)
KANG BINGQIANG (CN)
LIU RUIHONG (CN)
SONG HONGMEI (CN)
XUE TONGTONG (CN)
WANG JINGYI (CN)
ZHANG YITAO (CN)
JIANG XIAOLING (CN)
LIU CHUNCHI (CN)
KANG BINGQIANG (CN)
LIU RUIHONG (CN)
SONG HONGMEI (CN)
XUE TONGTONG (CN)
WANG JINGYI (CN)
Application Number:
PCT/CN2021/119002
Publication Date:
March 31, 2022
Filing Date:
September 17, 2021
Export Citation:
Assignee:
SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
A61K31/415; C07D231/10; A61P35/00; C07D231/54; C07D451/00; C07D487/04
Domestic Patent References:
| WO2020013803A1 | 2020-01-16 | |||
| WO2002094833A1 | 2002-11-28 | |||
| WO2009150547A2 | 2009-12-17 | |||
| WO2017035118A1 | 2017-03-02 | |||
| WO2018019106A1 | 2018-02-01 |
Foreign References:
| CN101062916A | 2007-10-31 | |||
| CN101528752A | 2009-09-09 | |||
| CN109415346A | 2019-03-01 | |||
| CN202011043288A | 2020-09-28 | |||
| US20190194198A1 | 2019-06-27 |
Other References:
M. ABID MASOOD ET AL.: "Lead Diversification 2: Application to P38, gMTP and lead compounds", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, 17 November 2011 (2011-11-17), pages 1255 - 1262, XP029121621, DOI: 10.1016/j.bmcl.2011.11.033
ACS MED. CHEM. LETT, vol. 9, 2018, pages 1117
NATURE, vol. 425, 2003, pages 577
PNAS, vol. 116, 2019, pages 9166
GOODMANGILMAN'S: "The Pharmacological Basis of Therapeutics", 1996, MCGRAW-HILL INTERNATIONAL EDITIONS
ACS MED. CHEM. LETT, vol. 9, 2018, pages 1117
NATURE, vol. 425, 2003, pages 577
PNAS, vol. 116, 2019, pages 9166
GOODMANGILMAN'S: "The Pharmacological Basis of Therapeutics", 1996, MCGRAW-HILL INTERNATIONAL EDITIONS
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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