A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME

Title:

A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME

Document Type and Number:

WIPO Patent Application WO2004064721

Kind Code:

A3

Abstract:

The present invention provides a novel pyrazolopyrimidine compound of the formula [I]: wherein R' is (A) a substituted aryl group, (B) an optionally substituted nitrogen-containing aliphatic heteromonocyclic group, (C) a substituted cyclo-lower alkyl group, (D) an optionally substituted amino group, or (E) a substituted heteroaryl group, R<2> is (a) an optionally substituted heteroaryl group or (b) an optionally substituted aryl group, Y is a single bond, a lower alkylene group or a lower alkenylene group, Z is a group of the formula: -CO-, -CH2-, -S02- or a group of the formula[II]: Q is a lower alkylene group, and q is an integer of 0 or 1 or a pharmaceutically acceptable sait thereof, which has a small conductance potassium channel (SK channel) blocking activity and is useful as a medicament and a process for preparing the same.

Inventors:

TAKAMURO IWAO (JP)
SEKINE YASUO (JP)
TSUBOI YASUNORI (JP)
NOGI KOUJI (JP)
TANIGUCHI HIROYUKI (JP)

Application Number:

PCT/JP2004/000617

Publication Date:

September 23, 2004

Filing Date:

January 23, 2004

Export Citation:

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Assignee:

TANABE SEIYAKU CO (JP)
TAKAMURO IWAO (JP)
SEKINE YASUO (JP)
TSUBOI YASUNORI (JP)
NOGI KOUJI (JP)
TANIGUCHI HIROYUKI (JP)

International Classes:

A61K6/00; A61K31/519; A61P1/00; A61P25/00; C07D487/04; C07D519/00; A61K; (IPC1-7): C07D487/04; C07D519/00; A61K31/519; A61P1/00; A61P25/00

Domestic Patent References:

WO2002079189A2

2002-10-10

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