Title:
PYRIMIDINE OR PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN PHARMACY
Document Type and Number:
WIPO Patent Application WO/2023/011505
Kind Code:
A1
Abstract:
A pyrimidine or pyridine derivative having a structure represented by formula (I), a preparation method therefor, a pharmaceutical composition containing same, a use thereof as an EGFR inhibitor, and a use thereof in the preparation of a drug for treating and/or preventing cancer, tumors, or metastatic diseases associated at least in part with EGFR exon 20 insertions, deletions, or other mutations, especially a use thereof in the preparation of a drug for treating and/or preventing hyperproliferative diseases and the induction of cell death disorders.
Inventors:
FENG TAO (CN)
ZHAO BAOWEI (CN)
ZHANG MINGMING (CN)
YANG SHUQUN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
ZHAO BAOWEI (CN)
ZHANG MINGMING (CN)
YANG SHUQUN (CN)
YU HONGPING (CN)
CHEN ZHUI (CN)
XU YAOCHANG (CN)
Application Number:
PCT/CN2022/109819
Publication Date:
February 09, 2023
Filing Date:
August 03, 2022
Export Citation:
Assignee:
ABBISKO THERAPEUTICS CO LTD (CN)
International Classes:
C07D209/04; A61K31/136; A61K31/167; A61K31/404; A61P35/00; C07D471/04
Domestic Patent References:
| WO2016070816A1 | 2016-05-12 | |||
| WO2016029839A1 | 2016-03-03 |
Foreign References:
| CN109328059A | 2019-02-12 | |||
| CN103702990A | 2014-04-02 | |||
| CN106928150A | 2017-07-07 | |||
| MD21040010A |
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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