Title:
PYRROLE AMIDOPYRIDONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/187123
Kind Code:
A1
Abstract:
Disclosed are a pyrrole amidopyridone represented by general formula I, or a pharmaceutically acceptable salt thereof, or an enantiomer, a diastereomer, a tautomer, a solvate, a polymorph, or a prodrug thereof, a preparation method therefor and use thereof in pharmacy, the definition of each group being as described in the description.
Inventors:
WAN HUIXIN (CN)
PAN JIANFENG (CN)
MA JINGUI (CN)
PAN JIANFENG (CN)
MA JINGUI (CN)
Application Number:
PCT/CN2020/078963
Publication Date:
September 24, 2020
Filing Date:
March 12, 2020
Export Citation:
Assignee:
SHANGHAI RINGENE BIOPHARMA CO LTD (CN)
International Classes:
C07D471/04; A61K31/437; A61K31/4523; A61K31/454; A61K31/496; A61K31/538; A61K31/5386; A61P1/00; A61P1/16; A61P1/18; A61P3/10; A61P7/06; A61P9/00; A61P9/10; A61P11/02; A61P11/06; A61P13/00; A61P13/12; A61P17/00; A61P17/06; A61P17/14; A61P19/02; A61P19/06; A61P21/04; A61P25/16; A61P25/28; A61P29/00; A61P31/10; A61P35/00; A61P35/02; A61P37/00; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
| WO2020020288A1 | 2020-01-30 | |||
| WO2014125408A2 | 2014-08-21 | |||
| WO2017177955A1 | 2017-10-19 |
Foreign References:
| CN110204543A | 2019-09-06 | |||
| CN110143961A | 2019-08-20 | |||
| CN110041253A | 2019-07-23 | |||
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Other References:
GREENWALD, R. B. ET AL., J. MED. CHEM., vol. A, B, 2000, pages 475
"Chiral Separations, Methods and Protocols, Methods in Molecular Biology", vol. 243, 2004
A.M. STALCUP, CHIRAL SEPARATIONS, ANNU. REV. ANAL. CHEM., vol. 3, 2010, pages 341 - 63
"VOGEL'S ENCYCLOPEDIA OF PRACTICAL ORGANIC CHEMISTRY 5.sup.TH ED.", 1991, LONGMAN SCIENTIFIC AND TECHNICAL LTD., pages: 809 - 816
HELLER, ACC. CHEM. RES., vol. 23, 1990, pages 128
SAULNIER, M. G. ET AL., BIOORG. MED. CHEM. LETT., vol. 4, 1994, pages 1985 - 1990
GREENE, T. W.P. G. M. WUTS: "The Pharmacological Basis of Therapeutics", 1999, MACK PUBLISHING CO.
See also references of EP 3967690A4
"Chiral Separations, Methods and Protocols, Methods in Molecular Biology", vol. 243, 2004
A.M. STALCUP, CHIRAL SEPARATIONS, ANNU. REV. ANAL. CHEM., vol. 3, 2010, pages 341 - 63
"VOGEL'S ENCYCLOPEDIA OF PRACTICAL ORGANIC CHEMISTRY 5.sup.TH ED.", 1991, LONGMAN SCIENTIFIC AND TECHNICAL LTD., pages: 809 - 816
HELLER, ACC. CHEM. RES., vol. 23, 1990, pages 128
SAULNIER, M. G. ET AL., BIOORG. MED. CHEM. LETT., vol. 4, 1994, pages 1985 - 1990
GREENE, T. W.P. G. M. WUTS: "The Pharmacological Basis of Therapeutics", 1999, MACK PUBLISHING CO.
See also references of EP 3967690A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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