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Title:
RADIOACTIVE PARTICLE, PREPARATION METHOD THEREFOR, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/228559
Kind Code:
A1
Abstract:
Provided is a radioactive particle, comprising a porous silicon dioxide particle and at least one type of radionuclide precipitate accommodated in the pores of the porous silicon dioxide particle. Said porous silicon dioxide particle is hydrophilic, and said radionuclide precipitate is formed by reacting positive ions with negative ions, said positive ions and/or negative ions containing radionuclides. The radioactive particle has a stable structure, is easy and practical, and can carry radionuclide precipitates containing different radionuclides. In addition, the release rate of the radionuclides is low, and the present invention has a wide application prospect. Also provided are a preparation method for the radioactive particle, and uses of the radioactive particles or the radioactive particles prepared using the preparation method therefor in medications for treating tumors.

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Inventors:
CHEN LIJUAN (CN)
JIN XIAOWEI (CN)
CAI QI (CN)
ZHANG JIALE (CN)
PENG TING (CN)
Application Number:
PCT/CN2020/088489
Publication Date:
November 19, 2020
Filing Date:
April 30, 2020
Export Citation:
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Assignee:
SHENZHEN DAXITA TECH CO LTD (CN)
International Classes:
A61K51/12; A61K47/02; A61K47/04; A61K51/02; A61P35/00; A61K101/00; A61K101/02; A61K103/00; A61K103/32
Foreign References:
US20020114763A12002-08-22
CN102182442A2011-09-14
CN106178006A2016-12-07
CN103480328A2014-01-01
CN102671219A2012-09-19
CN104394853A2015-03-04
CN106687146A2017-05-17
CN107715122A2018-02-23
CN101259290A2008-09-10
CN107715123A2018-02-23
Other References:
ANGLIN, EMILY J.: "Porous Silicon in Drug Delivery Devices and Materials", ADV DRUG DELIV REV., vol. 60, no. 11, 17 August 2008 (2008-08-17), XP022849511, DOI: 10.1016/j.addr.2008.03.017
Attorney, Agent or Firm:
SCIHEAD IP LAW FIRM (CN)
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