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Title:
RECTAL MUCOSAL ADMINISTRATION PREPARATION OF PULSATILLA CHINENSIS (BGE.) REGEL SAPONIN B4 AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/134159
Kind Code:
A1
Abstract:
A rectal mucosal administration preparation of Pulsatilla chinensis (Bge.) Regel saponin B4, comprising Pulsatilla chinensis (Bge.) Regel saponin B4 and a pharmaceutically acceptable substrate; the rectal mucosal administration preparation is one or two selected from among a rectal gel and a rectal suppository. Specifically, provided are a rectal gel of Pulsatilla chinensis (Bge.) Regel saponin B4, a rectal suppository of Pulsatilla chinensis (Bge.) Regel saponin B4 and preparation methods therefor. Compared with oral administration, the rectal mucosal administration preparation of Pulsatilla chinensis (Bge.) Regel saponin B4 has a lower effective dose, and has a better medicinal effect at the same dose.

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Inventors:
LIU QI (CN)
Application Number:
PCT/CN2018/071716
Publication Date:
July 11, 2019
Filing Date:
January 08, 2018
Export Citation:
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Assignee:
LIU QI (CN)
International Classes:
A61K9/06; A61K9/02; A61K31/704; A61K47/14; A61K47/32; A61P13/12
Foreign References:
CN105213410A2016-01-06
CN103446237A2013-12-18
CN105854021A2016-08-17
CN1903174A2007-01-31
CN105193705A2015-12-30
CN1903351A2007-01-31
CN105213410A2016-01-06
CN105535004A2016-05-04
CN201710551726A2017-07-07
Other References:
MA WEINA ; GU FUGEN: "The Research Progress of Medicinal Gels", PRACTICAL PHARMACY AND CLINICAL REMEDIES, vol. 17, no. 12, 15 December 2014 (2014-12-15), CN, pages 1624 - 1627, XP009522200, ISSN: 1673-0070, DOI: 10.14053/j.cnki.ppcr.2014.12.032
LIU, YAMIN ET AL.: "Mixed Fatty Acid Glyceride", PHARMACEUTICAL PREPARATION COMMON AUXILIARY MATERIALS, 31 January 1994 (1994-01-31), pages 219 - 220, XP009522212, ISBN: 7-5433-0568-2
See also references of EP 3738581A4
Attorney, Agent or Firm:
LEADING INTELLECTUAL PROPERTY FIRM (CN)
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