Title:
SELENIUM-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/246903
Kind Code:
A1
Abstract:
The present invention provides a selenium-containing heterocyclic compound with a structure represented by formula (I) or a pharmaceutically acceptable salt thereof or a stereoisomer thereof or a prodrug molecule thereof or a deuterated form thereof. The compound can be used as a KRAS G12D inhibitor for treating highly proliferative diseases, such as cancer.
Inventors:
DING KE (CN)
ZHANG XIN (CN)
CHAN SHINGPAN (CN)
WANG JIE (CN)
ZHANG ZHANG (CN)
GAO YUEYI (CN)
ZHANG XIN (CN)
CHAN SHINGPAN (CN)
WANG JIE (CN)
ZHANG ZHANG (CN)
GAO YUEYI (CN)
Application Number:
PCT/CN2023/101848
Publication Date:
December 28, 2023
Filing Date:
June 21, 2023
Export Citation:
Assignee:
UNIV JINAN (CN)
GUANGZHOU SALUSTIER BIOSCIENCES CO LTD (CN)
GUANGZHOU SALUSTIER BIOSCIENCES CO LTD (CN)
International Classes:
A61K31/517; C07D519/00; A61K31/519; A61P35/00; C07D421/14
Domestic Patent References:
| WO2022042630A1 | 2022-03-03 | |||
| WO2022015375A1 | 2022-01-20 | |||
| WO2022105855A1 | 2022-05-27 |
Foreign References:
| CN111170962A | 2020-05-19 | |||
| CN113754653A | 2021-12-07 | |||
| CN113999226A | 2022-02-01 | |||
| CN114615981A | 2022-06-10 |
Attorney, Agent or Firm:
GUANGZHOU PRIME IP LAW OFFICE (CN)
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