THE SEMI-SYNTHESIS OF BACCATIN III

Title:

THE SEMI-SYNTHESIS OF BACCATIN III

Document Type and Number:

WIPO Patent Application WO1999054322

Kind Code:

B1

Abstract:

This invention provides a process for the preparation of Baccatin III from a compound of formula (X) which comprises the steps of: (i) protecting the hydroxy group on a compound of Formula (X) at the 7-position or C9, or both C7 and C9 sequentially; (ii) oxidizing the resulting group at the C9 position; (iii) either: (a) sequentially deacylating the esters at positions C13 and C7 or, (b) simultaneously deacylating the esters at positions C13 and C7.

Inventors:

ZAMIR LOLITA (CA)
CARON GAETAN (CA)

Application Number:

PCT/CA1999/000328

Publication Date:

December 16, 1999

Filing Date:

April 20, 1999

Export Citation:

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Assignee:

ZAMIR LOLITA (CA)
CARON GAETAN (CA)

International Classes:

C07D305/14; (IPC1-7): C07D305/14

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