Title:
SHEET-LIKE CELL-CULTURED PRODUCT FOR REGENERATION OF GASTROINTESTINAL TRACT
Document Type and Number:
WIPO Patent Application WO/2020/022494
Kind Code:
A1
Abstract:
Provided in the present specification are: a sheet-like cell-cultured product for promoting healing of a hollow organ having a damaged area, in particular, tissues of duodenum; a method for producing the sheet-like cell-cultured product; a method for regenerating the damaged area of a hollow organ by using the sheet-like cell-cultured product; and the like.
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Inventors:
MARUYA YASUHIRO (JP)
MATSUMOTO RYO (JP)
KOBAYASHI SHINICHIRO (JP)
KANETAKA KENGO (JP)
EGUCHI SUSUMU (JP)
OHNITA KEN (JP)
HASHIGUCHI KEIICHI (JP)
OHASHI FUMIYA (JP)
MATSUMURA MASAKI (JP)
MATSUMOTO RYO (JP)
KOBAYASHI SHINICHIRO (JP)
KANETAKA KENGO (JP)
EGUCHI SUSUMU (JP)
OHNITA KEN (JP)
HASHIGUCHI KEIICHI (JP)
OHASHI FUMIYA (JP)
MATSUMURA MASAKI (JP)
Application Number:
PCT/JP2019/029479
Publication Date:
January 30, 2020
Filing Date:
July 26, 2019
Export Citation:
Assignee:
UNIV NAGASAKI (JP)
TERUMO CORP (JP)
TERUMO CORP (JP)
International Classes:
A61L27/38; A61L27/18; A61L27/22; A61L27/24; A61L27/36; A61L27/40; A61L27/52; C12N5/071; C12N5/077
Domestic Patent References:
| WO2010016469A1 | 2010-02-11 | |||
| WO2017130802A1 | 2017-08-03 | |||
| WO2017130802A1 | 2017-08-03 | |||
| WO2014185517A1 | 2014-11-20 |
Foreign References:
| JP2007528755A | 2007-10-18 | |||
| JP2016052271A | 2016-04-14 | |||
| JP2007528755A | 2007-10-18 | |||
| JP2007089442A | 2007-04-12 | |||
| JP2010081829A | 2010-04-15 | |||
| JP2011110368A | 2011-06-09 | |||
| JPH02211865A | 1990-08-23 | |||
| JP2003033177A | 2003-02-04 | |||
| JP2016052271A | 2016-04-14 | |||
| JP2014179151A | 2014-09-25 | |||
| JP2008173333A | 2008-07-31 | |||
| JP2009000511A | 2009-01-08 |
Other References:
TANAKA SHIRO; KANETAKA KENGO; FUJII MIO; ITO SHINICHIRO; SAKAI YUSUKE; KOBAYASHI SHINICHIRO; YAMANOUCHI KOSHO; FUJITA FUMIHIKO; KU: "Cell sheet technology for the regeneration of gastrointestinal tissue using a novel gastric perforation rat model", SURGERY TODAY, vol. 47, no. 1, 201660604, pages 114 - 21, XP036110590, ISSN: 0941-1291, DOI: 10.1007/s00595-016-1360-2
TAKAYUKI TANAKA; TAMOTSU KUROKI; TOMOHIKO ADACHI; SHINICHIRO ONO; AMANE KITASATO; MASATAKA HIRABARU; MITSUHISA TAKATSUKI; SUSUMU E: "Development of a novel rat model with pancreatic fistula and the prevention of this complication using tissue-engineered myoblast sheets", JOURNAL OF GASTROENTERLOGY, vol. 48, no. 9, 30 September 2013 (2013-09-30), pages 1081 - 9, XP055680016, ISSN: 0944-1174, DOI: 10.1007/s00535-012-0706-9
YASUHIRO MARUYA; NOBUO KANAI; SHINICHIRO KOBAYASHI; KURODO KOSHINO; TERUO OKANO; SUSUMU EGUCHI; MASAYUKI YAMATO: "Autologous adipose-derived stem cell sheets enhance the strength of intestinal anastomosis", REGEN REGENERATIVE THERAPY, vol. 7, 31 December 2017 (2017-12-31), pages 24 - 33, XP055680018, ISSN: 2352-3204, DOI: 10.1016/j.reth.2017.06.004
YUSUKE SAKAI, SUSUMU EGUCHI: "Tissue Repair Promotion and Functional Tissue Fabrication of Digestive Organ by Cell Sheets", MEMBRAME, vol. 43, no. 2, 28 February 2018 (2018-02-28), pages 34 - 39, XP009522353, ISSN: 0385-1036, DOI: 10.5360/membrane.43.34
MATTSUMOTO, AKIRA ET AL.: "Postoperative perforation prevention effect by implantation of autologous myoblast sheet using a duodenal mucosal separation model", PROGRAMS AND ABSTRACTS OF 18TH GENERAL MEETING OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE, 22 February 2019 (2019-02-22), pages 631, XP009522461, ISSN: 1347-7919
KANETAKA, KENGO ET AL.: "Development of medical care of autologous myoblast sheet for early duodenal cancer", REGENERATIVE MEDICINE, February 2019 (2019-02-01), pages 51, XP009522464, ISSN: 1347-7919
AKIRA MATISUMOTO : "A preclinical study using large animals for a method of implantation of autologous myoblast sheet to prevent perforation after alimentary tract surgery", April 2019 (2019-04-01), pages 1198, XP009522469, Retrieved from the Internet
HARAGUCHI ET AL., STEM CELLS TRANSL MED., vol. 1, no. 2, February 2012 (2012-02-01), pages 136 - 41
SAWA ET AL., SURG TODAY, vol. 42, no. 2, January 2012 (2012-01-01), pages 181 - 4
TANAKA ET AL., J GASTROENTEROL., vol. 48, no. 9, September 2013 (2013-09-01), pages 1081 - 9
TANAKA ET AL., SURG TODAY, vol. 47, no. 1, January 2017 (2017-01-01), pages 114 - 121
MAEKAWA S ET AL., SURG ENDSC, 2015
TAKIMOTO K ET AL., DIG ENDOSCO, 2014
FUJIHARA S ET AL., WORLD J GASTROENTEROL, 2016
ROSENDAAL ET AL., J CELL SCI., vol. 107, 1994, pages 29 - 37
GOODPASTER ET AL., J HISTOCHEM CYTOCHEM., vol. 56, no. 4, 2008, pages 347 - 58
See also references of EP 3741399A4
TAKAYUKI TANAKA; TAMOTSU KUROKI; TOMOHIKO ADACHI; SHINICHIRO ONO; AMANE KITASATO; MASATAKA HIRABARU; MITSUHISA TAKATSUKI; SUSUMU E: "Development of a novel rat model with pancreatic fistula and the prevention of this complication using tissue-engineered myoblast sheets", JOURNAL OF GASTROENTERLOGY, vol. 48, no. 9, 30 September 2013 (2013-09-30), pages 1081 - 9, XP055680016, ISSN: 0944-1174, DOI: 10.1007/s00535-012-0706-9
YASUHIRO MARUYA; NOBUO KANAI; SHINICHIRO KOBAYASHI; KURODO KOSHINO; TERUO OKANO; SUSUMU EGUCHI; MASAYUKI YAMATO: "Autologous adipose-derived stem cell sheets enhance the strength of intestinal anastomosis", REGEN REGENERATIVE THERAPY, vol. 7, 31 December 2017 (2017-12-31), pages 24 - 33, XP055680018, ISSN: 2352-3204, DOI: 10.1016/j.reth.2017.06.004
YUSUKE SAKAI, SUSUMU EGUCHI: "Tissue Repair Promotion and Functional Tissue Fabrication of Digestive Organ by Cell Sheets", MEMBRAME, vol. 43, no. 2, 28 February 2018 (2018-02-28), pages 34 - 39, XP009522353, ISSN: 0385-1036, DOI: 10.5360/membrane.43.34
MATTSUMOTO, AKIRA ET AL.: "Postoperative perforation prevention effect by implantation of autologous myoblast sheet using a duodenal mucosal separation model", PROGRAMS AND ABSTRACTS OF 18TH GENERAL MEETING OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE, 22 February 2019 (2019-02-22), pages 631, XP009522461, ISSN: 1347-7919
KANETAKA, KENGO ET AL.: "Development of medical care of autologous myoblast sheet for early duodenal cancer", REGENERATIVE MEDICINE, February 2019 (2019-02-01), pages 51, XP009522464, ISSN: 1347-7919
AKIRA MATISUMOTO : "A preclinical study using large animals for a method of implantation of autologous myoblast sheet to prevent perforation after alimentary tract surgery", April 2019 (2019-04-01), pages 1198, XP009522469, Retrieved from the Internet
HARAGUCHI ET AL., STEM CELLS TRANSL MED., vol. 1, no. 2, February 2012 (2012-02-01), pages 136 - 41
SAWA ET AL., SURG TODAY, vol. 42, no. 2, January 2012 (2012-01-01), pages 181 - 4
TANAKA ET AL., J GASTROENTEROL., vol. 48, no. 9, September 2013 (2013-09-01), pages 1081 - 9
TANAKA ET AL., SURG TODAY, vol. 47, no. 1, January 2017 (2017-01-01), pages 114 - 121
MAEKAWA S ET AL., SURG ENDSC, 2015
TAKIMOTO K ET AL., DIG ENDOSCO, 2014
FUJIHARA S ET AL., WORLD J GASTROENTEROL, 2016
ROSENDAAL ET AL., J CELL SCI., vol. 107, 1994, pages 29 - 37
GOODPASTER ET AL., J HISTOCHEM CYTOCHEM., vol. 56, no. 4, 2008, pages 347 - 58
See also references of EP 3741399A4
Attorney, Agent or Firm:
KUZUWA, Kiyoshi (JP)
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