Title:
SILANE-CONTAINING CONDENSED CYCLIC DIPEPTIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND METHOD FOR PRODUCING POLYPEPTIDE COMPOUND USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/190486
Kind Code:
A1
Abstract:
The present invention provides, as a novel compound that can be utilized for efficient synthesis or the like of a polypeptide comprising various amino acids, a silane-containing condensed cyclic dipeptide compound represented by formula (A). In formula (A), each of R11, R12, R13, R21, and R22 independently represents a hydrogen atom, a halogen atom, a hydroxyl group, a carboxyl group, a nitro group, a cyano group, or a thiol group, or a monovalent aliphatic hydrocarbon group, aromatic hydrocarbon group, or heterocyclic group that may have one or more substituents; and each of Ra1 and Ra2 independently represents a monovalent aliphatic hydrocarbon group or aromatic hydrocarbon group that may have one or more substituents.
Inventors:
YAMAMOTO HISASHI (JP)
HATTORI TOMOHIRO (JP)
HATTORI TOMOHIRO (JP)
Application Number:
PCT/JP2021/044773
Publication Date:
September 15, 2022
Filing Date:
December 06, 2021
Export Citation:
Assignee:
CHUBU UNIV EDUCATIONAL FOUNDATION (JP)
International Classes:
C07F7/18; C07C269/04; C07C271/22; C07C319/20; C07C323/51; C07C323/57; C07K1/06; C07K1/10; C07K5/06
Domestic Patent References:
| WO2021039901A1 | 2021-03-04 | |||
| WO2020262258A1 | 2020-12-30 | |||
| WO2010103857A1 | 2010-09-16 | |||
| WO2019069978A1 | 2019-04-11 | |||
| WO2017204144A1 | 2017-11-30 | |||
| WO2018199146A1 | 2018-11-01 | |||
| WO2018199147A1 | 2018-11-01 | |||
| WO2019208731A1 | 2019-10-31 |
Foreign References:
| JP2020040951W | 2020-10-30 | |||
| JP2020040960W | 2020-10-30 | |||
| JP2021002306W | 2021-01-22 |
Other References:
GERICKE ROBERT, GERLACH DANIELA, WAGLER JÖRG: "Ring-Strain-Formation Lewis Acidity? A Pentacoordinate Silacyclobutane Comprising Exclusively Equatorial Si−C BondsDedicated to Prof. Dr. Reinhold Tacke on the occasion of his 60th birthday.", ORGANOMETALLICS, AMERICAN CHEMICAL SOCIETY, vol. 28, no. 23, 14 December 2009 (2009-12-14), pages 6831 - 6834, XP055964776, ISSN: 0276-7333, DOI: 10.1021/om900741a
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ORG. PROCESS RES. DEV., vol. 20, no. 2, 2016, pages 140 - 177
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LAZAREVA, N.F. PESTUNOVICH, V.A. ALBANOV, A.I. VESNIN, M.G. VORONKOV, M.G.: "trans-Silylation of silatranes and 1,2-dimethyl-2-azasilatran-3-one by Si-substituted trimethoxysilanes", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM , NL, vol. 41, no. 24, 1 June 2000 (2000-06-01), Amsterdam , NL , pages 4823 - 4826, XP004205627, ISSN: 0040-4039, DOI: 10.1016/S0040-4039(00)00736-X
CHEM. REV., vol. 111, 2011, pages 6557 - 6602
ORG. PROCESS RES. DEV., vol. 20, no. 2, 2016, pages 140 - 177
CHEM. REV., vol. 116, 2016, pages 12029 - 12122
SCIENCE, vol. 256, 1992, pages 221 - 225
ANGEW. CHEM. INT. ED., vol. 45, 2006, pages 1248 - 1252
CHEM. EUR. J., vol. 25, 2019, pages 15091
ORG. LETT., vol. 22, 2020, pages 8039
CHEM. EUR. J, vol. 24, 2018, pages 7033
ROESNER ET AL., CHEM. SCI., vol. 10, 2019, pages 2465 - 2472
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
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